Size-controlled synthesis of polymerized DNA nanoparticles for targeted anticancer drug delivery

We synthesized size-tunable polymerized DNA nanoparticles (PDNs) for cancer-targeted drug delivery via sequential processes of rolling circle amplification, condensation, and layer-by-layer assembly. The PDNs selectively delivered anti-sense oligonucleotides to target cancer cells and exhibited size...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2019-04, Vol.55 (34), p.495-498
Hauptverfasser:	Nam, Keonwook, Kim, Taehyung, Kim, Young Min, Yang, Kyungjik, Choe, Deokyoung, Mensah, Lawrence B, Choi, Ki Young, Roh, Young Hoon
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Chemical synthesis Deoxyribonucleic acid DNA Drug delivery systems Gene expression Nanoparticles Oligonucleotides Polymerization
Online-Zugang:	Volltext
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