Dielectric properties of muscle and adipose tissue-mimicking solutions for microwave medical imaging applications
The aim of the present study was to synthesize mixture solutions which can accurately mimic the dielectric properties of biological tissues, specifically muscle and adipose tissues between 500 MHz and 50 GHz. Mixtures utilizing concentrations of bovine serum albumin (BSA) dissolved in phosphate buff...
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| Veröffentlicht in: | Physics in medicine & biology 2019-04, Vol.64 (9), p.095009-095009 |
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| container_title | Physics in medicine & biology |
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| creator | Pollacco, D A Conti, M Caligari Farrugia, L Wismayer, P Schembri Farina, L Sammut, C V |
| description | The aim of the present study was to synthesize mixture solutions which can accurately mimic the dielectric properties of biological tissues, specifically muscle and adipose tissues between 500 MHz and 50 GHz. Mixtures utilizing concentrations of bovine serum albumin (BSA) dissolved in phosphate buffered saline (PBS) and Ringer's solutions were synthesized to mimic in vivo and ex vivo muscle tissues. Solutions consisting of concentrations of peanut oil and Triton X-100 (TX) in PBS and Ringer's solutions were also synthesized to mimic in vivo and ex vivo adipose tissue. Results were then analysed and compared to measured dielectric properties of in vivo and ex vivo biological tissues from another previous study. Good agreement with said dielectric property measurements were obtained since the solutions from this study yielded low RMSE and RMSRE values. This implied that such solutions can be utilized in the construction of human body phantoms for narrowband and ultra-wideband microwave devices for near field breast cancer imaging. |
| doi_str_mv | 10.1088/1361-6560/ab0dda |
| format | Article |
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Mixtures utilizing concentrations of bovine serum albumin (BSA) dissolved in phosphate buffered saline (PBS) and Ringer's solutions were synthesized to mimic in vivo and ex vivo muscle tissues. Solutions consisting of concentrations of peanut oil and Triton X-100 (TX) in PBS and Ringer's solutions were also synthesized to mimic in vivo and ex vivo adipose tissue. Results were then analysed and compared to measured dielectric properties of in vivo and ex vivo biological tissues from another previous study. Good agreement with said dielectric property measurements were obtained since the solutions from this study yielded low RMSE and RMSRE values. 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Med. Biol</addtitle><description>The aim of the present study was to synthesize mixture solutions which can accurately mimic the dielectric properties of biological tissues, specifically muscle and adipose tissues between 500 MHz and 50 GHz. Mixtures utilizing concentrations of bovine serum albumin (BSA) dissolved in phosphate buffered saline (PBS) and Ringer's solutions were synthesized to mimic in vivo and ex vivo muscle tissues. Solutions consisting of concentrations of peanut oil and Triton X-100 (TX) in PBS and Ringer's solutions were also synthesized to mimic in vivo and ex vivo adipose tissue. Results were then analysed and compared to measured dielectric properties of in vivo and ex vivo biological tissues from another previous study. Good agreement with said dielectric property measurements were obtained since the solutions from this study yielded low RMSE and RMSRE values. This implied that such solutions can be utilized in the construction of human body phantoms for narrowband and ultra-wideband microwave devices for near field breast cancer imaging.</description><subject>adipose</subject><subject>Adipose Tissue - cytology</subject><subject>Adipose Tissue - radiation effects</subject><subject>Electric Impedance</subject><subject>Humans</subject><subject>microwave ablation</subject><subject>microwave imaging</subject><subject>Microwaves</subject><subject>Molecular Imaging - methods</subject><subject>muscle</subject><subject>Muscles - cytology</subject><subject>Muscles - radiation effects</subject><subject>Phantoms, Imaging</subject><subject>tissue mimicking solutions</subject><issn>0031-9155</issn><issn>1361-6560</issn><issn>1361-6560</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1v1TAQxC0Eoo_CnRPyDQ6E7jq24xxR-ZQqcYGz5dibyiWJUzsB8d_jxys9IU4rjX4z2hnGniO8QTDmAluNjVYaLtwAIbgH7HAvPWQHgBabHpU6Y09KuQFANEI-ZmctGCk73R_Y7btIE_ktR8_XnFbKW6TC08jnvfiJuFsCdyGuqRDfYik7NXOco_8el2te0rRvMS2Fjynzqub00_0gPlOI3k08zu76yLl1narwB33KHo1uKvTs7p6zbx_ef7381Fx9-fj58u1V42WHWxOM0VL1DgcMmlCgFOAokPODDqFV4MFAACcFQuiEVoSgRkFCjMah1O05e3XKrbVudyqbnWPxNE1uobQXK9D0qu27DisKJ7T-X0qm0a65vp5_WQR7HNoeV7XHVe1p6Gp5cZe-D7XtveHvshV4fQJiWu1N2vNSy_4v7-U_8HUerJa2t9ArgN6uYWx_A0jll20</recordid><startdate>20190430</startdate><enddate>20190430</enddate><creator>Pollacco, D A</creator><creator>Conti, M Caligari</creator><creator>Farrugia, L</creator><creator>Wismayer, P Schembri</creator><creator>Farina, L</creator><creator>Sammut, C V</creator><general>IOP Publishing</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-3723-6626</orcidid></search><sort><creationdate>20190430</creationdate><title>Dielectric properties of muscle and adipose tissue-mimicking solutions for microwave medical imaging applications</title><author>Pollacco, D A ; Conti, M Caligari ; Farrugia, L ; Wismayer, P Schembri ; Farina, L ; Sammut, C V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c471t-d886459a1b1d6e121420aedeacb6dd350c080d0a4210d7265e105f2e22f8a1463</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>adipose</topic><topic>Adipose Tissue - cytology</topic><topic>Adipose Tissue - radiation effects</topic><topic>Electric Impedance</topic><topic>Humans</topic><topic>microwave ablation</topic><topic>microwave imaging</topic><topic>Microwaves</topic><topic>Molecular Imaging - methods</topic><topic>muscle</topic><topic>Muscles - cytology</topic><topic>Muscles - radiation effects</topic><topic>Phantoms, Imaging</topic><topic>tissue mimicking solutions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pollacco, D A</creatorcontrib><creatorcontrib>Conti, M Caligari</creatorcontrib><creatorcontrib>Farrugia, L</creatorcontrib><creatorcontrib>Wismayer, P Schembri</creatorcontrib><creatorcontrib>Farina, L</creatorcontrib><creatorcontrib>Sammut, C V</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Physics in medicine & biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pollacco, D A</au><au>Conti, M Caligari</au><au>Farrugia, L</au><au>Wismayer, P Schembri</au><au>Farina, L</au><au>Sammut, C V</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dielectric properties of muscle and adipose tissue-mimicking solutions for microwave medical imaging applications</atitle><jtitle>Physics in medicine & biology</jtitle><stitle>PMB</stitle><addtitle>Phys. 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| ispartof | Physics in medicine & biology, 2019-04, Vol.64 (9), p.095009-095009 |
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| source | MEDLINE; Institute of Physics Journals |
| subjects | adipose Adipose Tissue - cytology Adipose Tissue - radiation effects Electric Impedance Humans microwave ablation microwave imaging Microwaves Molecular Imaging - methods muscle Muscles - cytology Muscles - radiation effects Phantoms, Imaging tissue mimicking solutions |
| title | Dielectric properties of muscle and adipose tissue-mimicking solutions for microwave medical imaging applications |
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