Dielectric properties of muscle and adipose tissue-mimicking solutions for microwave medical imaging applications

The aim of the present study was to synthesize mixture solutions which can accurately mimic the dielectric properties of biological tissues, specifically muscle and adipose tissues between 500 MHz and 50 GHz. Mixtures utilizing concentrations of bovine serum albumin (BSA) dissolved in phosphate buff...

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Veröffentlicht in:Physics in medicine & biology 2019-04, Vol.64 (9), p.095009-095009
Hauptverfasser: Pollacco, D A, Conti, M Caligari, Farrugia, L, Wismayer, P Schembri, Farina, L, Sammut, C V
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Sprache:eng
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Zusammenfassung:The aim of the present study was to synthesize mixture solutions which can accurately mimic the dielectric properties of biological tissues, specifically muscle and adipose tissues between 500 MHz and 50 GHz. Mixtures utilizing concentrations of bovine serum albumin (BSA) dissolved in phosphate buffered saline (PBS) and Ringer's solutions were synthesized to mimic in vivo and ex vivo muscle tissues. Solutions consisting of concentrations of peanut oil and Triton X-100 (TX) in PBS and Ringer's solutions were also synthesized to mimic in vivo and ex vivo adipose tissue. Results were then analysed and compared to measured dielectric properties of in vivo and ex vivo biological tissues from another previous study. Good agreement with said dielectric property measurements were obtained since the solutions from this study yielded low RMSE and RMSRE values. This implied that such solutions can be utilized in the construction of human body phantoms for narrowband and ultra-wideband microwave devices for near field breast cancer imaging.
ISSN:0031-9155
1361-6560
1361-6560
DOI:10.1088/1361-6560/ab0dda