Control of Steroid Synthesis in Adrenal Fasciculata Cells

The control of steroid synthesis in adrenal fasciculata cells is considered in terms of two types of control by ACTH: 1) control of cholesterol availability to inner mitochondrial cytochrome P-450scc. This process controls total steroid synthesis and is rapidly activated by ACTH. The several steps i...

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Veröffentlicht in:	Endocrine research 1986, Vol.12 (4), p.315-350
Hauptverfasser:	Jefcoate, Colin R., Mcnamara, Brian C., Dibartolomeis, Michael J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex - metabolism Adrenocorticotropic Hormone - metabolism Animals Binding, Competitive Cardiolipins - pharmacology Cholesterol - metabolism Cytochrome P-450 Enzyme System - metabolism Hexanes - pharmacology Isoenzymes - metabolism Kinetics Mitochondria - metabolism Models, Molecular Pregnenolone - biosynthesis Protein Conformation Steroids - biosynthesis
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