Correlation between S100A11 and the TGF-β 1 /SMAD4 pathway and its effects on the proliferation and apoptosis of pancreatic cancer cell line PANC-1

S100A11 as a S100 protein family member has been documented to play dual-direction regulation over cancer cell proliferation. We explored the role of S100A11 in the proliferation and apoptosis of pancreatic cancer cell line PANC-1 and the potential mechanisms involving the TGF-β /SMAD4/p21 pathway....

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Veröffentlicht in:	Molecular and cellular biochemistry 2019-01, Vol.450 (1-2), p.53
Hauptverfasser:	Ji, Yi-Fei, Li, Tao, Jiang, Feng, Ni, Wen-Kai, Guan, Cheng-Qi, Liu, Zhao-Xiu, Lu, Cui-Hua, Ni, Run-Zhou, Wu, Wei, Xiao, Ming-Bing
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cell Line, Tumor Cell Proliferation Cyclin-Dependent Kinase Inhibitor p21 Female Humans Male Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Pancreatic Neoplasms - genetics Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - pathology S100 Proteins - genetics S100 Proteins - metabolism Signal Transduction Smad4 Protein - genetics Smad4 Protein - metabolism Transforming Growth Factor beta1 - genetics Transforming Growth Factor beta1 - metabolism
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