Human Urokinase Gene is Located on the Long Arm of Chromosome 10

Urokinase is one of the two plasminogen activators that catalyze the conversion of inactive plasminogen to plasmin. By combining somatic cell genetics, in situ hybridization, and Southern hybridization, we localized the human urokinase gene on the distal third of the long arm (q24-qter) of chromosom...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1985-07, Vol.82 (13), p.4448-4452
Hauptverfasser:	Tripputi, Pasquale, Blasi, Francesco, Verde, Pasquale, Cannizzaro, Linda A., Emanuel, Beverly S., Croce, Carlo M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chromosome Mapping Chromosomes Chromosomes, Human, 6-12 and X Classical genetics, quantitative genetics, hybrids DNA DNA probes DNA Restriction Enzymes - metabolism Fundamental and applied biological sciences. Psychology Genes Genetics of eukaryotes. Biological and molecular evolution Human Human chromosomes Human genetics Humans Hybridity In situ hybridization Karyotyping Nucleic Acid Hybridization Plasminogen activators Somatic cells Urokinase-Type Plasminogen Activator - genetics
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Zusammenfassung:	Urokinase is one of the two plasminogen activators that catalyze the conversion of inactive plasminogen to plasmin. By combining somatic cell genetics, in situ hybridization, and Southern hybridization, we localized the human urokinase gene on the distal third of the long arm (q24-qter) of chromosome 10.
ISSN:	0027-8424 1091-6490
DOI:	10.1073/pnas.82.13.4448