Beyond R 0 Maximisation: On Pathogen Evolution and Environmental Dimensions
A widespread tenet is that evolution of pathogens maximises their basic reproduction ratio, R . The breakdown of this principle is typically discussed as exception. Here, we argue that a radically different stance is needed, based on evolutionarily stable strategy (ESS) arguments that take account o...
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Veröffentlicht in: | Trends in ecology & evolution (Amsterdam) 2018-06, Vol.33 (6), p.458 |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | A widespread tenet is that evolution of pathogens maximises their basic reproduction ratio, R
. The breakdown of this principle is typically discussed as exception. Here, we argue that a radically different stance is needed, based on evolutionarily stable strategy (ESS) arguments that take account of the 'dimension of the environmental feedback loop'. The R
maximisation paradigm requires this feedback loop to be one-dimensional, which notably excludes pathogen diversification. By contrast, almost all realistic ecological ingredients of host-pathogen interactions (density-dependent mortality, multiple infections, limited cross-immunity, multiple transmission routes, host heterogeneity, and spatial structure) will lead to multidimensional feedbacks. |
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ISSN: | 1872-8383 |
DOI: | 10.1016/j.tree.2018.02.004 |