Herpes Simplex Virus Type 1 Human Cervical Dorsal Root Ganglionitis

We present a case of a 34-year-old right-handed Caucasian male with chronic occipital neuralgia refractory to medical therapies and minimally invasive pain procedures who underwent surgical cervical dorsal root ganglionectomy which completely relieved his headaches. The histopathological and immunoh...

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Veröffentlicht in:Case reports in neurology 2017-08, Vol.9 (2), p.188-194
Hauptverfasser: Valyi-Nagy, Tibor, Rathore, Jaivir S., Rakic, Andrei M., Rathore, Ranvir S., Jain, Paavani, Slavin, Konstantin V.
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Sprache:eng
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Zusammenfassung:We present a case of a 34-year-old right-handed Caucasian male with chronic occipital neuralgia refractory to medical therapies and minimally invasive pain procedures who underwent surgical cervical dorsal root ganglionectomy which completely relieved his headaches. The histopathological and immunohistochemical findings of the resected cervical dorsal root ganglia were consistent with active herpes simplex virus type 1 (HSV-1) infection causing ganglionitis. To the best of our knowledge, this case represents the first histopathologically proven HSV-1 cervical dorsal root ganglionitis in humans. This case provides an insight into a possible etiology of occipital neuralgia.
ISSN:1662-680X
1662-680X
DOI:10.1159/000479146