Determination of fumonisin B 1 levels in body fluids and hair from piglets fed fumonisin B 1 -contaminated diets

The levels of fumonisin B (FB ) residues in plasma, urine, feces and hair from 24 piglets fed FB -contaminated diets containing 3.1, 6.1 or 9.0 μg FB .g for 28 days were determined using liquid chromatography coupled to mass spectrometry (LC-MS/MS). The levels of FB in plasma, urine, feces and pooled hair (n = 3) samples varied from 0.15 to 1.08 μg.L , 16.09-75.01 μg.L , 1.87-13.89 μg.g and 2.08-8.09 ng.g , respectively. Significant correlations (r = 0.808-0.885; P 14 days). The possibility to evaluate hair as a biomarker of fumonisin exposure was established, although further studies are needed to provide physiologically based toxicokinetics of residual FB in the pig hair.