Nonalcoholic Steatohepatitis

Nonalcoholic steatohepatitis (NASH) has become a major cause of cirrhosis and liver-related deaths worldwide. NASH is strongly associated with obesity and the metabolic syndrome, conditions that cause lipid accumulation in hepatocytes (hepatic steatosis). It is not well understood why some, but not...

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Veröffentlicht in:	Annual review of medicine 2017-01, Vol.68 (1), p.85-98
Hauptverfasser:	Suzuki, Ayako, Diehl, Anna Mae
Format:	Artikel
Sprache:	eng
Schlagworte:	adaptive mechanisms Cell Death hepatic fibrosis Hepatitis - etiology hepatocyte damage Hepatocytes - pathology Hepatocytes - physiology Humans Lipid Metabolism lipotoxicity Liver - metabolism Liver - pathology Liver Cirrhosis - etiology Liver diseases Non-alcoholic Fatty Liver Disease - complications Non-alcoholic Fatty Liver Disease - metabolism Non-alcoholic Fatty Liver Disease - pathology nonalcoholic fatty liver disease Obesity Pathogenesis
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