Surveillance provides insight into epidemiology and spectrum of culture-confirmed mycobacterial disease in children

BACKGROUND: Longer-term tuberculosis (TB) drug resistance surveillance among children is rare. We determined the prevalence of drug resistance among children with culture-confirmed TB from 2011 to 2013, compared these results with four previous consecutive 2-year periods and documented other mycobac...

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Veröffentlicht in:	The international journal of tuberculosis and lung disease 2016-09, Vol.20 (9), p.1249-1256
Hauptverfasser:	Schaaf, H. S., Garcia-Prats, A. J., du Preez, K., Rautenbach, C., Hesseling, A. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Retroviral Agents - therapeutic use Antitubercular Agents - therapeutic use Child Child, Preschool Children Coinfection - drug therapy Coinfection - epidemiology Drug Resistance Epidemiological Monitoring Female HIV Infections - drug therapy HIV Infections - epidemiology Humans Infant Isoniazid - therapeutic use Male Mycobacteria Mycobacterium bovis - drug effects Mycobacterium bovis - isolation & purification Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - isolation & purification Nontuberculous Mycobacteria - drug effects Prevalence Rifampin - therapeutic use South Africa - epidemiology Surveillance Tuberculosis Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Multidrug-Resistant - epidemiology Tuberculosis, Multidrug-Resistant - transmission
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Beschreibung
Zusammenfassung:	BACKGROUND: Longer-term tuberculosis (TB) drug resistance surveillance among children is rare. We determined the prevalence of drug resistance among children with culture-confirmed TB from 2011 to 2013, compared these results with four previous consecutive 2-year periods and documented other mycobacterial isolates identified.METHOD: Surveillance study of mycobacterial culture in all children aged
ISSN:	1027-3719 1815-7920
DOI:	10.5588/ijtld.15.0051