An ion signal responsive dynamic protein nano-spring constructed by high ordered host-guest recognition

An ion signal responsive dynamic protein nano-spring constructed by high ordered host-guest recognition

A protein self-assembly nano-spring was developed through host-guest interactions between cucurbit[8]uril and tripeptide FGG tags of fusion protein FGG-recoverin-GST. Fine control of the conformational changes of the Ca 2+ -responsive domain allows for a 50% stretch of the protein nano-spring as it...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2016-01, Vol.52 (14), p.2924-2927
Hauptverfasser: Si, Chengye, Li, Jiaxi, Luo, Quan, Hou, Chunxi, Pan, Tiezheng, Li, Hongbin, Liu, Junqiu
Format: Artikel
Sprache:eng
Schlagworte:
Construction
Dynamics
Microscopy, Atomic Force
Nanostructure
Nanostructures
Proteins
Proteins - chemistry
Recognition
Self assembly
Switches
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Beschreibung
Zusammenfassung:A protein self-assembly nano-spring was developed through host-guest interactions between cucurbit[8]uril and tripeptide FGG tags of fusion protein FGG-recoverin-GST. Fine control of the conformational changes of the Ca 2+ -responsive domain allows for a 50% stretch of the protein nano-spring as it switches from the contracted state to the extended state. A Ca 2+ responsive protein self-assembly nano-spring was developed through host-guest interactions between cucurbit[8]uril and tripeptide FGG tags of fusion protein FGG-recoverin-GST.
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc10373h