Novel FGG variant (γ339C→S) confirms importance of the γ326-339 disulphide bond for plasma expression of newly synthesised fibrinogen

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Bibliographische Detailangaben
Veröffentlicht in:	Thrombosis and haemostasis 2015-04, Vol.113 (4), p.903
Hauptverfasser:	Brennan, Stephen O, Laurie, Andrew, Smith, Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Afibrinogenemia - blood Afibrinogenemia - diagnosis Afibrinogenemia - genetics Blood Coagulation Tests Blood Loss, Surgical - prevention & control Disulfides - metabolism DNA Mutational Analysis Female Fibrinogen - biosynthesis Fibrinogen - genetics Fibrinogens, Abnormal - biosynthesis Fibrinogens, Abnormal - genetics Genetic Predisposition to Disease Humans Middle Aged Mutation N-Acetylneuraminic Acid - metabolism Phenotype Postoperative Hemorrhage - blood Postoperative Hemorrhage - genetics Postoperative Hemorrhage - prevention & control Protein Conformation Structure-Activity Relationship
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