Treatment of advanced testicular cancer

Two patients with stage II, 12 patients with stage III advanced testicular cancer, were treated with a combination of CDDP, vinblastine and bleomycin. Four of the cases (28.6%) achieved a complete response and 6 (42.9%) achieved a partial response. The over all response rate was 71.4%. After CR, 2 c...

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Veröffentlicht in:	Hinyokika kiyo. Acta urologica Japonica 1987-01, Vol.33 (1), p.47
Hauptverfasser:	Murase, T, Takashi, M, Sobashima, T, Shimoji, T, Miyake, K, Mitsuya, H
Format:	Artikel
Sprache:	jpn
Schlagworte:	Adult Antineoplastic Combined Chemotherapy Protocols - therapeutic use Bleomycin - administration & dosage Cisplatin - administration & dosage Drug Administration Schedule Dysgerminoma - drug therapy Humans Male Neoplasms, Germ Cell and Embryonal - drug therapy Prognosis Teratoma - drug therapy Testicular Neoplasms - drug therapy Vinblastine - administration & dosage
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Beschreibung
Zusammenfassung:	Two patients with stage II, 12 patients with stage III advanced testicular cancer, were treated with a combination of CDDP, vinblastine and bleomycin. Four of the cases (28.6%) achieved a complete response and 6 (42.9%) achieved a partial response. The over all response rate was 71.4%. After CR, 2 cases (50%) showed relapse. Although the treatment confirms some efficacy of the drug regimen, the prognosis is poor in bulky metastasis. Early induction therapy with etoposide is necessary in cases of high volume metastasis.
ISSN:	0018-1994