The Role of the Macrophage in the Development of Aortic Dissection

The Role of the Macrophage in the Development of Aortic Dissection

In a recent report, Del Porto et al. addressed the role that MMP-12, in particular, plays in the degradation of elastin, fibronectin, and collagen leading to the development of thoracic aortic dissection, and hypothesized that MMP-12, in addition to VEGF and MCP-1 is a potentially measureable predic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cardiology 2014-01, Vol.127 (2), p.121-122
Hauptverfasser: Usman, Asad, Massad, Malek G.
Format: Artikel
Sprache:eng
Schlagworte:
Aneurysm, Dissecting - etiology
Aortic Aneurysm, Thoracic - etiology
Cellular biology
Coronary vessels
Editorial Comment
Female
Humans
Macrophages - physiology
Male
Proteases
Proteins
Vascular endothelial growth factor
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:In a recent report, Del Porto et al. addressed the role that MMP-12, in particular, plays in the degradation of elastin, fibronectin, and collagen leading to the development of thoracic aortic dissection, and hypothesized that MMP-12, in addition to VEGF and MCP-1 is a potentially measureable prediction molecule and hopefully clinically targetable in the future to prevent thoracic aortic aneurysms.
ISSN:0008-6312
1421-9751
DOI:10.1159/000356872