Idiopathic Fibrosing Alveolitis: A Review with Emphasis on Ultrastructural and Immunohistochemical Features

Idiopathic Fibrosing Alveolitis: A Review with Emphasis on Ultrastructural and Immunohistochemical Features

Fibrosing alveolitis is a usually chronic pulmonary disease affecting middle-aged men and women and causing progressive dyspnea. This review discusses the nosologic, etiologic, immunopathogenic, histologic, immunohistochemical and ultrastructural features of this condition. A hypothesis is presented...

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Veröffentlicht in:Ultrastructural pathology 1985, Vol.9 (3-4), p.345-372
Hauptverfasser: Hammar, Samuel P., Winterbauer, Richard H., Bockus, Dawn, Remington, Franque, Friedman, Susan
Format: Artikel
Sprache:eng
Schlagworte:
Acquired Immunodeficiency Syndrome - pathology
AIDS/HIV
Biopsy
electron microscopy
Female
Fibronectins - analysis
fibrosing alveolitis
Growth Substances - analysis
Histocytochemistry
Humans
immunohistochemistry
Interferon Type I - analysis
Keratins - analysis
Lung - pathology
Male
Microcirculation
Microscopy, Electron
Molecular Weight
Pleura - pathology
pulmonary fibrosis
Pulmonary Fibrosis - pathology
T-Lymphocytes - analysis
tubuloreticular structures
vascular damage
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Beschreibung
Zusammenfassung:Fibrosing alveolitis is a usually chronic pulmonary disease affecting middle-aged men and women and causing progressive dyspnea. This review discusses the nosologic, etiologic, immunopathogenic, histologic, immunohistochemical and ultrastructural features of this condition. A hypothesis is presented suggesting microvascular damage as the primary pathologic change in cases associated with collagen vascular diseases and viral pneumonia.
ISSN:0191-3123
1521-0758
DOI:10.3109/01913128509074587