Pou2f3/Skn-1a Is Necessary for the Generation or Differentiation of Solitary Chemosensory Cells in the Anterior Nasal Cavity
Solitary chemosensory cells in the non-neuronal epithelium of the anterior nasal cavity have bitter taste cell-like molecular characteristics and are involved in the detection of noxious substances. Here, we demonstrate that Pou2f3/Skn-1a, which is necessary for generation of sweet, umami, and bitte...
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| Veröffentlicht in: | Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2013, Vol.77 (10), p.2154-2156 |
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| container_end_page | 2156 |
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| container_issue | 10 |
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| container_title | Bioscience, biotechnology, and biochemistry |
| container_volume | 77 |
| creator | OHMOTO, Makoto YAMAGUCHI, Tatsuya YAMASHITA, Junpei BACHMANOV, Alexander A HIROTA, Junji MATSUMOTO, Ichiro |
| description | Solitary chemosensory cells in the non-neuronal epithelium of the anterior nasal cavity have bitter taste cell-like molecular characteristics and are involved in the detection of noxious substances. Here, we demonstrate that Pou2f3/Skn-1a, which is necessary for generation of sweet, umami, and bitter taste cells, is also necessary for the generation or differentiation of solitary chemosensory cells. |
| doi_str_mv | 10.1271/bbb.130454 |
| format | Article |
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| identifier | ISSN: 0916-8451 |
| ispartof | Bioscience, biotechnology, and biochemistry, 2013, Vol.77 (10), p.2154-2156 |
| issn | 0916-8451 1347-6947 |
| language | eng |
| recordid | cdi_pubmed_primary_24096675 |
| source | J-STAGE Free; MEDLINE; Oxford University Press Journals All Titles (1996-Current); Freely Accessible Japanese Titles; EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry |
| subjects | Animals Cell Differentiation differentiation Epithelial Cells - cytology Epithelial Cells - metabolism Gene Knockout Techniques Mice Nasal Cavity - cytology Octamer Transcription Factors - deficiency Octamer Transcription Factors - genetics Octamer Transcription Factors - metabolism Pou2f3 solitary chemosensory cell taste cell transcription factor |
| title | Pou2f3/Skn-1a Is Necessary for the Generation or Differentiation of Solitary Chemosensory Cells in the Anterior Nasal Cavity |
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