Accelerating Effect of Soy Peptides Containing Collagen Peptides on Type I and III Collagen Levels in Rat Skin

Two weeks of feeding soy peptides containing 2% collagen peptides increased the levels of type I and III tropocollagen and their mRNAs. In contrast, the diet did not increase the mRNA levels of rat hyaluronan synthases, serine palmitoyltransferase (the rate-limiting enzyme of ceramide synthesis), an...

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Veröffentlicht in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2012, Vol.76 (8), p.1549-1551
Hauptverfasser: INOUE, Yoshiki, ITOH, Hitomi, AOKI, Marie, OGAWA, Sachie, YAMANE, Takumi, BABA, Toshimitsu, TACHIBANA, Nobuhiko, KOHNO, Mitsutaka, OISHI, Yuichi, KOBAYASHI-HATTORI, Kazuo
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Sprache:eng
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Zusammenfassung:Two weeks of feeding soy peptides containing 2% collagen peptides increased the levels of type I and III tropocollagen and their mRNAs. In contrast, the diet did not increase the mRNA levels of rat hyaluronan synthases, serine palmitoyltransferase (the rate-limiting enzyme of ceramide synthesis), and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (the key enzyme of cholesterol synthesis). These results suggest that feeding of soy peptides with collagen peptides specifically enhanced the tropocollagen level in the skin.
ISSN:0916-8451
1347-6947
DOI:10.1271/bbb.120088