Intracranial hemorrhage as initial presentation of biliary atresia: two cases report

Biliary atresia in infants occasionally presents as intracranial, nasal or gastrointestinal bleeding, instead of the classical triad of jaundice, acholia and choluria. We present two female infants aged four and two months, who were hospitalized with convulsive episode, cephalohematoma and drowsines...

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Veröffentlicht in:Archivos argentinos de pediatría 2011-12, Vol.109 (6), p.119
Hauptverfasser: Mariani, Alicia, Parma, Gabriela, Sánchez, Viviana, Strático, Roxana, Bignon, Horacio, Bartuluchi, Marcelo, Vera, Fabián, Bazán, Silvana, Selandari, Jorge
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Sprache:spa
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Zusammenfassung:Biliary atresia in infants occasionally presents as intracranial, nasal or gastrointestinal bleeding, instead of the classical triad of jaundice, acholia and choluria. We present two female infants aged four and two months, who were hospitalized with convulsive episode, cephalohematoma and drowsiness. Computed tomography findings were subdural hemorrhage in one patient and intraventricular and parenchymal bleeding in the other one. At admission they have history, clinical and laboratory signs of cholestasis of unknown etiology. The patient with subdural hemorrhage required surgical drainage. The other girl with intraventricular and parenchymal bleeding received vitamin K and no surgery. Biliary atresia was diagnosed and treated in both girls. At six months both had an adequate neurological outcome and required liver transplantation at one year old. Biliary atresia should be considered in all infants with sudden acute bleeding and cholestasis.
ISSN:1668-3501
DOI:10.5546/aap.2011.e119