Randomized Controlled Trial of a High Dose of Oral Erythromycin for the Treatment of Feeding Intolerance in Preterm Infants

Randomized Controlled Trial of a High Dose of Oral Erythromycin for the Treatment of Feeding Intolerance in Preterm Infants

Objectives: To evaluate the effectiveness of high-dose erythromycin to treat feeding intolerance in preterm infants predominantly fed milk formula. Design: This study is a prospective randomized controlled trial on 60 premature infants suffering from feeding intolerance. Thirty infants were given or...

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Veröffentlicht in:Neonatology (Basel, Switzerland) Switzerland), 2011-01, Vol.100 (3), p.290-294
Hauptverfasser: Mansi, Yasmeen, Abdelaziz, Nabil, Ezzeldin, Zahraa, Ibrahim, Rania
Format: Artikel
Sprache:eng
Schlagworte:
Dose-Response Relationship, Drug
Double-Blind Method
Enteral Nutrition
Erythromycin - therapeutic use
Female
Gastrointestinal Agents - therapeutic use
Gastrointestinal Diseases - drug therapy
Gastrointestinal Motility - drug effects
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases - drug therapy
Male
Prospective Studies
Short Communication
Time Factors
Treatment Outcome
Weight Gain - drug effects
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Zusammenfassung:Objectives: To evaluate the effectiveness of high-dose erythromycin to treat feeding intolerance in preterm infants predominantly fed milk formula. Design: This study is a prospective randomized controlled trial on 60 premature infants suffering from feeding intolerance. Thirty infants were given oral erythromycin ethylsuccinate at a dose of 50 mg/kg/day for 10 days or until they reached full enteral feeds. Randomization was stratified according to gestational age
ISSN:1661-7800
1661-7819
DOI:10.1159/000327536