Gold nanorods 3D-supercrystals as surface enhanced Raman scattering spectroscopy substrates for the rapid detection of scrambled prions

Gold nanorods 3D-supercrystals as surface enhanced Raman scattering spectroscopy substrates for the rapid detection of scrambled prions

Highly organized supercrystals of Au nanorods with plasmonic antennae enhancement of electrical field have made possible fast direct detection of prions in complex biological media such as serum and blood. The nearly perfect three-dimensional organization of nanorods render these systems excellent s...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2011-05, Vol.108 (20), p.8157-8161
Hauptverfasser: Alvarez-Puebla, Ramón A, Agarwal, Ashish, Manna, Pramit, Khanal, Bishnu P, Aldeanueva-Potel, Paula, Carbó-Argibay, Enrique, Pazos-Pérez, Nicolas, Vigderman, Leonid, Zubarev, Eugene R, Kotov, Nicholas A, Liz-Marzán, Luis M
Format: Artikel
Sprache:eng
Schlagworte:
antennae
Blood plasma
blood serum
Cleaning
Crystallization
Crystals
electric field
Electric fields
gold
Gold - chemistry
Humans
Lasers
Material films
Nanorods
Nanotubes
Physical Sciences
Plasma spectra
Prions
Prions - analysis
Prions - blood
Raman scattering
Raman spectroscopy
rapid methods
Scattering
Spectrum analysis
Spectrum Analysis, Raman - methods
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Highly organized supercrystals of Au nanorods with plasmonic antennae enhancement of electrical field have made possible fast direct detection of prions in complex biological media such as serum and blood. The nearly perfect three-dimensional organization of nanorods render these systems excellent surface enhanced Raman scattering spectroscopy substrates with uniform electric field enhancement, leading to reproducibly high enhancement factor in the desirable spectral range.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.1016530108