α-Terpineol reduces nociceptive behavior in mice

α-Terpineol reduces nociceptive behavior in mice

Context: α-Terpineol (TPN) is a monoterpenoid alcohol present in the essential oils of several species of the Eucalyptus genus (Myrtaceae). Objective: TPN was assessed for its antinociceptive activity in rodents. Materials and methods: The antinociceptive effect of TPN was examined using the acetic...

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Veröffentlicht in:Pharmaceutical biology 2011-06, Vol.49 (6), p.583-586
Hauptverfasser: Quintans-Júnior, Lucindo J., Oliveira, Makson G.B., Santana, Michele F., Santana, Marilia T., Guimarães, Adriana G., Siqueira, Jullyana S., De Sousa, Damião P., Almeida, Reinaldo N.
Format: Artikel
Sprache:eng
Schlagworte:
Analgesics - pharmacology
Animals
capsaicin
Cyclohexenes - pharmacology
Drug Evaluation, Preclinical
formalin
glutamate
Male
Mice
monoterpene
Monoterpenes - pharmacology
Motor Activity - drug effects
pain
Pain Measurement - methods
Rotarod Performance Test - methods
α-terpineol
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Zusammenfassung:Context: α-Terpineol (TPN) is a monoterpenoid alcohol present in the essential oils of several species of the Eucalyptus genus (Myrtaceae). Objective: TPN was assessed for its antinociceptive activity in rodents. Materials and methods: The antinociceptive effect of TPN was examined using the acetic acid writhing reflex, formalin, glutamate, and capsaicin-induced nociception tests. Results: TPN produced a significant (P 
ISSN:1388-0209
1744-5116
DOI:10.3109/13880209.2010.529616