Dermoscopy of Pigmented Lesions of the Vulva: A Retrospective Morphological Study

Background: The dermoscopic patterns of pigmented skin tumors are influenced by the body site. Objective: To evaluate the clinical and dermoscopic features associated with pigmented vulvar lesions. Methods: Retrospective analysis of clinical and dermoscopic images of vulvar lesions. The χ 2 test was...

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Veröffentlicht in:Dermatology (Basel) 2011-01, Vol.222 (2), p.157-166
Hauptverfasser: Ferrari, Angela, Zalaudek, Iris, Argenziano, Giuseppe, Buccini, Pierluigi, De Simone, Paola, Silipo, Vitaliano, Eibenschutz, Laura, Mariani, Giustino, Covello, Renato, Sperduti, Isabella, Mariani, Luciano, Catricalà, Caterina
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Sprache:eng
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Zusammenfassung:Background: The dermoscopic patterns of pigmented skin tumors are influenced by the body site. Objective: To evaluate the clinical and dermoscopic features associated with pigmented vulvar lesions. Methods: Retrospective analysis of clinical and dermoscopic images of vulvar lesions. The χ 2 test was used to test the association between clinical data and histopathological diagnosis. Results: A total of 42 (32.8%) melanocytic and 86 (67.2%) nonmelanocytic vulvar lesions were analyzed. Nevi significantly prevailed in younger women compared with melanomas and melanosis and exhibited most commonly a globular/cobblestone (51.3%) and a mixed (21.6%) pattern. Dermoscopically all melanomas showed a multicomponent pattern. Melanotic macules showed clinical overlapping features with melanoma, but their dermoscopic patterns differed significantly from those observed in melanomas. Conclusion: The diagnosis and management of pigmented vulvar lesions should be based on a good clinicodermoscopic correlation. Dermoscopy may be helpful in the differentiation of solitary melanotic macules from early melanoma.
ISSN:1018-8665
1421-9832
DOI:10.1159/000323409