Inhibitory activity against urease of quercetin glycosides isolated from Allium cepa and Psidium guajava

Methanolic extracts of edible plants and seaweeds were tested for their inhibitory activity against Jack bean urease. Quercetin-4′-O-β-D-glucopyranoside was isolated from Allium cepa as a urease inhibitor with an IC 50 value of 190 μM-. Quercetin and two quercetin glycosides, avicularin and guaijave...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2010, Vol.74 (4), p.878-880
Hauptverfasser:	Shabana, S., Osaka Prefecture Univ., Sakai (Japan), Kawai, A, Kai, K, Akiyama, K, Hayashi, H
Format:	Artikel
Sprache:	eng
Schlagworte:	ALLIUM CEPA Biological and medical sciences edible plant ENZYME INHIBITORS flavonoid FLAVONOIDE FLAVONOIDES FLAVONOIDS Flavonoids - pharmacology Fundamental and applied biological sciences. Psychology http://www.fao.org/aos/agrovoc#c_2599 http://www.fao.org/aos/agrovoc#c_281 http://www.fao.org/aos/agrovoc#c_2964 http://www.fao.org/aos/agrovoc#c_35288 http://www.fao.org/aos/agrovoc#c_6315 http://www.fao.org/aos/agrovoc#c_8092 INHIBIDORES DE ENZIMAS INHIBITEUR D'ENZYME Methanol Onions - chemistry Psidium - chemistry PSIDIUM GUAJAVA QUERCETIN Quercetin - pharmacology quercetin glycoside QUERCETINA QUERCETINE Rutin UREASA UREASE urease inhibitor
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Zusammenfassung:	Methanolic extracts of edible plants and seaweeds were tested for their inhibitory activity against Jack bean urease. Quercetin-4′-O-β-D-glucopyranoside was isolated from Allium cepa as a urease inhibitor with an IC 50 value of 190 μM-. Quercetin and two quercetin glycosides, avicularin and guaijaverin, were isolated from Psidium guajava as urease inhibitors with respective IC 50 values of 80 μM-, 140 μM-, and 120 μM-.
ISSN:	0916-8451 1347-6947
DOI:	10.1271/bbb.90895