Search for Cellular Phosphorylation Products of D-Allose
The all-cis hexose D-allose, fed to hamster fibroblast cultures over 14-20 hr, brings about a striking down-regulation of hexose transport. This down-regulation by allose is inhibited by 2,4-dinitrophenol. By using D-[14C]allose and thin-layer chromatography, two types of products accumulated that h...
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| Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 1991-02, Vol.88 (4), p.1504-1505 |
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| container_title | Proceedings of the National Academy of Sciences - PNAS |
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| creator | Ullrey, Donna B. Kalckar, Herman M. |
| description | The all-cis hexose D-allose, fed to hamster fibroblast cultures over 14-20 hr, brings about a striking down-regulation of hexose transport. This down-regulation by allose is inhibited by 2,4-dinitrophenol. By using D-[14C]allose and thin-layer chromatography, two types of products accumulated that have been identified as allose and allose phosphate. We suspect that allose phosphate might be the down-regulator. |
| doi_str_mv | 10.1073/pnas.88.4.1504 |
| format | Article |
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This down-regulation by allose is inhibited by 2,4-dinitrophenol. By using D-[14C]allose and thin-layer chromatography, two types of products accumulated that have been identified as allose and allose phosphate. We suspect that allose phosphate might be the down-regulator.</description><identifier>ISSN: 0027-8424</identifier><identifier>EISSN: 1091-6490</identifier><identifier>DOI: 10.1073/pnas.88.4.1504</identifier><identifier>PMID: 1996350</identifier><identifier>CODEN: PNASA6</identifier><language>eng</language><publisher>Washington, DC: National Academy of Sciences of the United States of America</publisher><subject>550501 - Metabolism- Tracer Techniques ; ANIMAL CELLS ; ANIMALS ; BASIC BIOLOGICAL SCIENCES ; Biological and medical sciences ; Biotransformation ; CARBOHYDRATES ; CARBON 14 COMPOUNDS ; Carbon Radioisotopes ; Cell extracts ; Cell Line ; Cell physiology ; CHEMICAL REACTIONS ; CHROMATOGRAPHY ; Chromatography, Thin Layer ; CONNECTIVE TISSUE CELLS ; Cricetinae ; Cricetulus ; Down regulation ; Ethanol ; FIBROBLASTS ; Fundamental and applied biological sciences. Psychology ; Glucose - metabolism ; HAMSTERS ; HEXOSES ; ISOTOPE APPLICATIONS ; Kinetics ; LABELLED COMPOUNDS ; Lung ; MAMMALS ; Membrane and intracellular transports ; MEMBRANE TRANSPORT ; METABOLISM ; Molecular and cellular biology ; MONOSACCHARIDES ; ORGANIC COMPOUNDS ; Phosphatases ; Phosphates ; PHOSPHORYLATION ; Radioisotope Dilution Technique ; RODENTS ; SACCHARIDES ; SEPARATION PROCESSES ; SOMATIC CELLS ; THIN-LAYER CHROMATOGRAPHY ; TRACER TECHNIQUES ; VERTEBRATES</subject><ispartof>Proceedings of the National Academy of Sciences - PNAS, 1991-02, Vol.88 (4), p.1504-1505</ispartof><rights>Copyright 1991 The National Academy of Sciences of the United States of America</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c580t-2028609b2a6469f77b7b9489642c4dbe856f9468d8036c5d89385319bb8aae523</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://www.pnas.org/content/88/4.cover.gif</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/2356024$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/2356024$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,723,776,780,799,881,27901,27902,53766,53768,57992,58225</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19824137$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1996350$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/6010254$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Ullrey, Donna B.</creatorcontrib><creatorcontrib>Kalckar, Herman M.</creatorcontrib><title>Search for Cellular Phosphorylation Products of D-Allose</title><title>Proceedings of the National Academy of Sciences - PNAS</title><addtitle>Proc Natl Acad Sci U S A</addtitle><description>The all-cis hexose D-allose, fed to hamster fibroblast cultures over 14-20 hr, brings about a striking down-regulation of hexose transport. This down-regulation by allose is inhibited by 2,4-dinitrophenol. By using D-[14C]allose and thin-layer chromatography, two types of products accumulated that have been identified as allose and allose phosphate. We suspect that allose phosphate might be the down-regulator.</description><subject>550501 - Metabolism- Tracer Techniques</subject><subject>ANIMAL CELLS</subject><subject>ANIMALS</subject><subject>BASIC BIOLOGICAL SCIENCES</subject><subject>Biological and medical sciences</subject><subject>Biotransformation</subject><subject>CARBOHYDRATES</subject><subject>CARBON 14 COMPOUNDS</subject><subject>Carbon Radioisotopes</subject><subject>Cell extracts</subject><subject>Cell Line</subject><subject>Cell physiology</subject><subject>CHEMICAL REACTIONS</subject><subject>CHROMATOGRAPHY</subject><subject>Chromatography, Thin Layer</subject><subject>CONNECTIVE TISSUE CELLS</subject><subject>Cricetinae</subject><subject>Cricetulus</subject><subject>Down regulation</subject><subject>Ethanol</subject><subject>FIBROBLASTS</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Glucose - metabolism</subject><subject>HAMSTERS</subject><subject>HEXOSES</subject><subject>ISOTOPE APPLICATIONS</subject><subject>Kinetics</subject><subject>LABELLED COMPOUNDS</subject><subject>Lung</subject><subject>MAMMALS</subject><subject>Membrane and intracellular transports</subject><subject>MEMBRANE TRANSPORT</subject><subject>METABOLISM</subject><subject>Molecular and cellular biology</subject><subject>MONOSACCHARIDES</subject><subject>ORGANIC COMPOUNDS</subject><subject>Phosphatases</subject><subject>Phosphates</subject><subject>PHOSPHORYLATION</subject><subject>Radioisotope Dilution Technique</subject><subject>RODENTS</subject><subject>SACCHARIDES</subject><subject>SEPARATION PROCESSES</subject><subject>SOMATIC CELLS</subject><subject>THIN-LAYER CHROMATOGRAPHY</subject><subject>TRACER TECHNIQUES</subject><subject>VERTEBRATES</subject><issn>0027-8424</issn><issn>1091-6490</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkc2LFDEQxYMo67h69aTQCHrrtvLZCXhZxk9YcEE9h3Q6bfeS6YxJWtz_3gw9jiN4qsP7vXpFPYSeYmgwtPT1fjapkbJhDebA7qENBoVrwRTcRxsA0taSEfYQPUrpFgAUl3CBLrBSgnLYIPnFmWjHagix2jrvF29idTOGtB9DvPMmT2GubmLoF5tTFYbqbX3lfUjuMXowGJ_ck-O8RN_ev_u6_Vhff_7waXt1XduSlGsCRApQHTGCCTW0bdd2ikklGLGs75zkYlBMyF4CFZb3UlHJKVZdJ41xnNBL9Gbdu1-6neutm3M0Xu_jtDPxTgcz6X-VeRr19_BTcwysLfYXqz2kPOlkp-zsaMM8O5u1AAyEswK9OmbE8GNxKevdlGz5hpldWJKWwArVigI2K2hjSCm64XQHBn2oQx_q0FJqpg91FMPz8-v_4uv_i_7yqJtkjR-ime2UzjBJGKbt2YWH_X_kU44eFu-z-5XPAv8LFv3Zqt-mHOIJIJQLIIz-Bp_wsu0</recordid><startdate>19910215</startdate><enddate>19910215</enddate><creator>Ullrey, Donna B.</creator><creator>Kalckar, Herman M.</creator><general>National Academy of Sciences of the United States of America</general><general>National Acad Sciences</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope><scope>5PM</scope></search><sort><creationdate>19910215</creationdate><title>Search for Cellular Phosphorylation Products of D-Allose</title><author>Ullrey, Donna B. ; Kalckar, Herman M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c580t-2028609b2a6469f77b7b9489642c4dbe856f9468d8036c5d89385319bb8aae523</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>550501 - Metabolism- Tracer Techniques</topic><topic>ANIMAL CELLS</topic><topic>ANIMALS</topic><topic>BASIC BIOLOGICAL SCIENCES</topic><topic>Biological and medical sciences</topic><topic>Biotransformation</topic><topic>CARBOHYDRATES</topic><topic>CARBON 14 COMPOUNDS</topic><topic>Carbon Radioisotopes</topic><topic>Cell extracts</topic><topic>Cell Line</topic><topic>Cell physiology</topic><topic>CHEMICAL REACTIONS</topic><topic>CHROMATOGRAPHY</topic><topic>Chromatography, Thin Layer</topic><topic>CONNECTIVE TISSUE CELLS</topic><topic>Cricetinae</topic><topic>Cricetulus</topic><topic>Down regulation</topic><topic>Ethanol</topic><topic>FIBROBLASTS</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Glucose - metabolism</topic><topic>HAMSTERS</topic><topic>HEXOSES</topic><topic>ISOTOPE APPLICATIONS</topic><topic>Kinetics</topic><topic>LABELLED COMPOUNDS</topic><topic>Lung</topic><topic>MAMMALS</topic><topic>Membrane and intracellular transports</topic><topic>MEMBRANE TRANSPORT</topic><topic>METABOLISM</topic><topic>Molecular and cellular biology</topic><topic>MONOSACCHARIDES</topic><topic>ORGANIC COMPOUNDS</topic><topic>Phosphatases</topic><topic>Phosphates</topic><topic>PHOSPHORYLATION</topic><topic>Radioisotope Dilution Technique</topic><topic>RODENTS</topic><topic>SACCHARIDES</topic><topic>SEPARATION PROCESSES</topic><topic>SOMATIC CELLS</topic><topic>THIN-LAYER CHROMATOGRAPHY</topic><topic>TRACER TECHNIQUES</topic><topic>VERTEBRATES</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ullrey, Donna B.</creatorcontrib><creatorcontrib>Kalckar, Herman M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ullrey, Donna B.</au><au>Kalckar, Herman M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Search for Cellular Phosphorylation Products of D-Allose</atitle><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle><addtitle>Proc Natl Acad Sci U S A</addtitle><date>1991-02-15</date><risdate>1991</risdate><volume>88</volume><issue>4</issue><spage>1504</spage><epage>1505</epage><pages>1504-1505</pages><issn>0027-8424</issn><eissn>1091-6490</eissn><coden>PNASA6</coden><abstract>The all-cis hexose D-allose, fed to hamster fibroblast cultures over 14-20 hr, brings about a striking down-regulation of hexose transport. This down-regulation by allose is inhibited by 2,4-dinitrophenol. By using D-[14C]allose and thin-layer chromatography, two types of products accumulated that have been identified as allose and allose phosphate. We suspect that allose phosphate might be the down-regulator.</abstract><cop>Washington, DC</cop><pub>National Academy of Sciences of the United States of America</pub><pmid>1996350</pmid><doi>10.1073/pnas.88.4.1504</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Proceedings of the National Academy of Sciences - PNAS, 1991-02, Vol.88 (4), p.1504-1505 |
| issn | 0027-8424 1091-6490 |
| language | eng |
| recordid | cdi_pubmed_primary_1996350 |
| source | Jstor Complete Legacy; MEDLINE; PubMed Central; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry |
| subjects | 550501 - Metabolism- Tracer Techniques ANIMAL CELLS ANIMALS BASIC BIOLOGICAL SCIENCES Biological and medical sciences Biotransformation CARBOHYDRATES CARBON 14 COMPOUNDS Carbon Radioisotopes Cell extracts Cell Line Cell physiology CHEMICAL REACTIONS CHROMATOGRAPHY Chromatography, Thin Layer CONNECTIVE TISSUE CELLS Cricetinae Cricetulus Down regulation Ethanol FIBROBLASTS Fundamental and applied biological sciences. Psychology Glucose - metabolism HAMSTERS HEXOSES ISOTOPE APPLICATIONS Kinetics LABELLED COMPOUNDS Lung MAMMALS Membrane and intracellular transports MEMBRANE TRANSPORT METABOLISM Molecular and cellular biology MONOSACCHARIDES ORGANIC COMPOUNDS Phosphatases Phosphates PHOSPHORYLATION Radioisotope Dilution Technique RODENTS SACCHARIDES SEPARATION PROCESSES SOMATIC CELLS THIN-LAYER CHROMATOGRAPHY TRACER TECHNIQUES VERTEBRATES |
| title | Search for Cellular Phosphorylation Products of D-Allose |
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