Familial Furunculosis Associated with Community-Acquired Leukocidin-Positive Methicillin-Susceptible Staphylococcus aureus ST152

Panton-Valentine leukocidin (PVL) is associated with staphylococcal skin and pulmonary infections. Community dissemination of PVL-producing Staphylococcus aureus strains constitutes a public health concern. Family transmission and spread of community-acquired leukocidin-positive methicillin-suscepti...

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Veröffentlicht in:	Journal of Clinical Microbiology 2010-01, Vol.48 (1), p.329-332
Hauptverfasser:	Pérez-Roth, E, Alcoba-Flórez, J, López-Aguilar, C, Gutiérrez-González, I, Rivero-Pérez, B, Méndez-Álvarez, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Bacterial Proteins - biosynthesis Bacterial Typing Techniques Bacteriology Biological and medical sciences Case Reports Child Cluster Analysis Community-Acquired Infections - epidemiology Community-Acquired Infections - microbiology Community-Acquired Infections - transmission DNA Fingerprinting Family Health Fundamental and applied biological sciences. Psychology Furunculosis - epidemiology Furunculosis - microbiology Furunculosis - transmission Genotype Humans Leukocidins - biosynthesis Male Methicillin-Resistant Staphylococcus aureus - classification Methicillin-Resistant Staphylococcus aureus - genetics Methicillin-Resistant Staphylococcus aureus - isolation & purification Microbiology Miscellaneous Polymorphism, Restriction Fragment Length Staphylococcal Infections - epidemiology Staphylococcal Infections - microbiology Staphylococcal Infections - transmission Staphylococcus aureus Virulence Factors - biosynthesis
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Zusammenfassung:	Panton-Valentine leukocidin (PVL) is associated with staphylococcal skin and pulmonary infections. Community dissemination of PVL-producing Staphylococcus aureus strains constitutes a public health concern. Family transmission and spread of community-acquired leukocidin-positive methicillin-susceptible S. aureus ST152 isolates associated with severe clinical symptoms are herein described. Remarkably, ST152 isolates usually are methicillin resistant.
ISSN:	0095-1137 1098-660X
DOI:	10.1128/JCM.00622-09