Is cannabis a vulnerability factor in schizophrenic disorders

Links between cannabis and schizophrenic disorders are ages old. Cannabis has effects that are close to the symptoms of schizophrenia. Abuse and dependence are more frequent in schizophrenic population than in general population. This consumption is a gravity factor in terms of prognosis. It acceler...

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Veröffentlicht in:	Archives de pédiatrie : organe officiel de la Société française de pédiatrie 2009-09, Vol.16 (9), p.1302
1. Verfasser:	Laqueille, X
Format:	Artikel
Sprache:	fre
Schlagworte:	Age of Onset Evidence-Based Medicine Humans Marijuana Abuse - complications Marijuana Abuse - diagnosis Marijuana Abuse - epidemiology Paris - epidemiology Prevalence Prognosis Psychiatric Status Rating Scales Risk Factors Schizophrenia - complications Schizophrenia - diagnosis Schizophrenia - epidemiology Severity of Illness Index
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Beschreibung
Zusammenfassung:	Links between cannabis and schizophrenic disorders are ages old. Cannabis has effects that are close to the symptoms of schizophrenia. Abuse and dependence are more frequent in schizophrenic population than in general population. This consumption is a gravity factor in terms of prognosis. It accelerates the first psychotic decompensations. Studies by cohorts of experts allow for the affirmation that cannabis is a risk factor in schizophrenic disorders, with an effect dose and depending, above all in the case of consumption before the age of 15. This observation is in line with the greatest diffusion of cannabinoid receivers in the encephalon of schizophrenic subjects and their role in cerebral maturity during puberty.
ISSN:	1769-664X
DOI:	10.1016/j.arcped.2009.03.016