The phosphorylation of survivin Thr34 by p34cdc2 in carcinogenesis of oral submucous fibrosis

Survivin is a crucial node molecule involved in apoptosis, cell division and drug discovery. Up-regulation of survivin in the tissues of oral submucous fibrosis (OSF) and oral squamous cell carcinoma (OSCC) originated from OSF has already been demonstrated. Survivin Thr34 phosphorylation is involved...

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Veröffentlicht in:	Oncology reports 2008-11, Vol.20 (5), p.1085-1091
Hauptverfasser:	Zhou, Shanghui, Li, Lili, Jian, Xinchun, Ou, Xinrong, Jiang, Haiying, Yao, Zhigang, Xu, Chunjiao, Peng, Jieying
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blotting, Western Carcinoma, Squamous Cell - metabolism CDC2 Protein Kinase - metabolism Cell Transformation, Neoplastic - metabolism Humans Immunohistochemistry Immunoprecipitation Inhibitor of Apoptosis Proteins Medical sciences Microtubule-Associated Proteins - metabolism Mouth Neoplasms - metabolism Neoplasm Proteins - metabolism Oral Submucous Fibrosis - metabolism Otorhinolaryngology. Stomatology Phosphorylation Precancerous Conditions - metabolism Tumors Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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