Impact of spermatozoid head anomalies as predictor factor of non-determined infertility

To evaluate fertilization and pregnancy rates, and pregnancy outcome in women diagnosed with non-determined infertility, and its correlation with sperm head morphology anomalies. Retrospective study (ANOVA) including 126 patients diagnosed with non-determined infertility, attended from January 2002 to December 2006, admitted to embryo transference fertilization program, both conventional in vitro and intracytoplasmatic sperm injection. Spermatic morphology was analyzed in accordance with Kruger's strict criterion. All of patients had spermatic morphology higher than 5%, with 7.17% average. They were divided into three groups, in accordance with sperm head morphology anomalies percentage: group 1, less than 30%; group 2, 31 to 39%, and group 3, more than 40%. All of them had oocyte insemination: half conventional in vitro and half intracytoplasmatic sperm injection. Group 1 had higher percentage of fertilization, over groups 2 and 3 (65.44, 49.5 and 57.23%, respectively; p = 0.002). Abortion numbers showed meaningful differences too; group 1 had no abortions, meanwhile groups 2 and 3 had 30.77 and 22.22%, respectively. Evaluation of sperm head morphology anomalies must be a prognostic factor in pregnancy evolution, in women with nondetermined infertility.