Weekly docetaxel vs. docetaxel-based combination chemotherapy as second-line treatment of advanced non-small-cell lung cancer patients The DISTAL-2 randomized trial

Doublet chemotherapy is more effective than single-agent as first line treatment of advanced non-small-cell lung cancer (NSCLC). No reliable information instead is available on the effect of doublets in second line treatment. The aim of DISTAL-2 study was to compare two doublets containing docetaxel...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Lung cancer (Amsterdam, Netherlands) Netherlands), 2009-02, Vol.63 (2), p.251-258
Hauptverfasser:	GEBBIA, Vittorio, GRIDELLI, Cesare, PERRONE, Francesco, MORABITO, Alessandro, VERUSIO, Claudio, FRONTINI, Luciano, AITINI, Enrico, DANIELE, Bruno, GAMUCCI, Teresa, MANCUSO, Gianfranco, DI MAIO, Massimo, GALLO, Ciro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - psychology Female Humans Lung Neoplasms - drug therapy Lung Neoplasms - mortality Lung Neoplasms - psychology Male Medical sciences Medication Adherence Middle Aged Pneumology Quality of Life Survival Rate Taxoids - administration & dosage Tumors Tumors of the respiratory system and mediastinum
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Doublet chemotherapy is more effective than single-agent as first line treatment of advanced non-small-cell lung cancer (NSCLC). No reliable information instead is available on the effect of doublets in second line treatment. The aim of DISTAL-2 study was to compare two doublets containing docetaxel with single agent docetaxel as second line treatment of patients with NSCLC (ClinicalTrials.gov id.:.NCT00345059). NSCLC patients, aged
ISSN:	0169-5002 1872-8332
DOI:	10.1016/j.lungcan.2008.05.027