Intra-alveolar haemorrhage without renal damage as the initial presenting feature of Goodpasture's syndrome: case report and review of literature

Isolated pulmonary involvement in Goodpasture's syndrome is exceptionally described. We report a 36-year-old woman with pulmonary haemorrhage and review 28 additional cases of the literature. In fact, these patients had often mild urine abnormalities and constant glomerular lesions. Antiglomeru...

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Veröffentlicht in:La revue de medecine interne 2008-12, Vol.29 (12), p.1038
Hauptverfasser: Lê Quang, C, Delèvaux, I, Trouillier, S, André, M, Souweine, B, Tridon, A, Cordier, J-F, Aumaître, O
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container_issue 12
container_start_page 1038
container_title La revue de medecine interne
container_volume 29
creator Lê Quang, C
Delèvaux, I
Trouillier, S
André, M
Souweine, B
Tridon, A
Cordier, J-F
Aumaître, O
description Isolated pulmonary involvement in Goodpasture's syndrome is exceptionally described. We report a 36-year-old woman with pulmonary haemorrhage and review 28 additional cases of the literature. In fact, these patients had often mild urine abnormalities and constant glomerular lesions. Antiglomerular basement membrane antibodies testing should be systematically ordered in patients presenting with alveolar haemorrhage. Goodpasture's syndrome without renal abnormality could be an early stage of the disease with a better prognosis.
doi_str_mv 10.1016/j.revmed.2008.03.001
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subjects Adolescent
Adrenal Cortex Hormones - administration & dosage
Adrenal Cortex Hormones - therapeutic use
Adult
Anti-Glomerular Basement Membrane Disease - diagnosis
Anti-Glomerular Basement Membrane Disease - drug therapy
Anti-Glomerular Basement Membrane Disease - immunology
Anti-Glomerular Basement Membrane Disease - pathology
Anti-Glomerular Basement Membrane Disease - therapy
Autoantibodies - analysis
Biopsy
Bronchoalveolar Lavage
Cyclophosphamide - administration & dosage
Cyclophosphamide - therapeutic use
Drug Therapy, Combination
Female
Follow-Up Studies
Glomerular Basement Membrane - immunology
Glomerular Basement Membrane - pathology
Hemorrhage - diagnosis
Hemorrhage - etiology
Humans
Immunosuppressive Agents - administration & dosage
Immunosuppressive Agents - therapeutic use
Lung Diseases - diagnostic imaging
Lung Diseases - etiology
Male
Plasma Exchange
Prognosis
Pulmonary Alveoli
Radiography, Thoracic
Time Factors
Tomography, X-Ray Computed
Treatment Outcome
title Intra-alveolar haemorrhage without renal damage as the initial presenting feature of Goodpasture's syndrome: case report and review of literature
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