Intra-alveolar haemorrhage without renal damage as the initial presenting feature of Goodpasture's syndrome: case report and review of literature
Isolated pulmonary involvement in Goodpasture's syndrome is exceptionally described. We report a 36-year-old woman with pulmonary haemorrhage and review 28 additional cases of the literature. In fact, these patients had often mild urine abnormalities and constant glomerular lesions. Antiglomeru...
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Veröffentlicht in: | La revue de medecine interne 2008-12, Vol.29 (12), p.1038 |
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creator | Lê Quang, C Delèvaux, I Trouillier, S André, M Souweine, B Tridon, A Cordier, J-F Aumaître, O |
description | Isolated pulmonary involvement in Goodpasture's syndrome is exceptionally described. We report a 36-year-old woman with pulmonary haemorrhage and review 28 additional cases of the literature. In fact, these patients had often mild urine abnormalities and constant glomerular lesions. Antiglomerular basement membrane antibodies testing should be systematically ordered in patients presenting with alveolar haemorrhage. Goodpasture's syndrome without renal abnormality could be an early stage of the disease with a better prognosis. |
doi_str_mv | 10.1016/j.revmed.2008.03.001 |
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We report a 36-year-old woman with pulmonary haemorrhage and review 28 additional cases of the literature. In fact, these patients had often mild urine abnormalities and constant glomerular lesions. Antiglomerular basement membrane antibodies testing should be systematically ordered in patients presenting with alveolar haemorrhage. 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We report a 36-year-old woman with pulmonary haemorrhage and review 28 additional cases of the literature. In fact, these patients had often mild urine abnormalities and constant glomerular lesions. Antiglomerular basement membrane antibodies testing should be systematically ordered in patients presenting with alveolar haemorrhage. Goodpasture's syndrome without renal abnormality could be an early stage of the disease with a better prognosis.</description><subject>Adolescent</subject><subject>Adrenal Cortex Hormones - administration & dosage</subject><subject>Adrenal Cortex Hormones - therapeutic use</subject><subject>Adult</subject><subject>Anti-Glomerular Basement Membrane Disease - diagnosis</subject><subject>Anti-Glomerular Basement Membrane Disease - drug therapy</subject><subject>Anti-Glomerular Basement Membrane Disease - immunology</subject><subject>Anti-Glomerular Basement Membrane Disease - pathology</subject><subject>Anti-Glomerular Basement Membrane Disease - therapy</subject><subject>Autoantibodies - analysis</subject><subject>Biopsy</subject><subject>Bronchoalveolar Lavage</subject><subject>Cyclophosphamide - administration & dosage</subject><subject>Cyclophosphamide - therapeutic use</subject><subject>Drug Therapy, Combination</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Glomerular Basement Membrane - immunology</subject><subject>Glomerular Basement Membrane - pathology</subject><subject>Hemorrhage - diagnosis</subject><subject>Hemorrhage - etiology</subject><subject>Humans</subject><subject>Immunosuppressive Agents - administration & dosage</subject><subject>Immunosuppressive Agents - therapeutic use</subject><subject>Lung Diseases - diagnostic imaging</subject><subject>Lung Diseases - etiology</subject><subject>Male</subject><subject>Plasma Exchange</subject><subject>Prognosis</subject><subject>Pulmonary Alveoli</subject><subject>Radiography, Thoracic</subject><subject>Time Factors</subject><subject>Tomography, X-Ray Computed</subject><subject>Treatment Outcome</subject><issn>0248-8663</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kMtOwzAURL0A0VL4A4S8Y5XgR-rE7FAFpVIlNrCubuKbxlUSR7bbqp_BH5PyWM3MkWYWQ8gdZylnXD3uUo-HDk0qGCtSJlPG-AWZMpEVSaGUnJDrEHZspIzrKzLhxTwXIldT8rXqo4cE2gO6FjxtADvnfQNbpEcbG7eP1GMPLTXQnSEEGhuktrfRjnTwGLCPtt_SGiHuPVJX06VzZoBwjg-BhlNvvOvwiVYQcJwbnI8UejPag8XjudHaiP6nf0Mua2gD3v7pjHy-vnws3pL1-3K1eF4nA5c6JrrKtVRVkSuRl2gyYyRyIedVxkCAqUowcwnalLou6wx0VUEhlGJaasO0LuWM3P_uDvtyvG4zeNuBP23-v5HfPLlq_w</recordid><startdate>200812</startdate><enddate>200812</enddate><creator>Lê Quang, C</creator><creator>Delèvaux, I</creator><creator>Trouillier, S</creator><creator>André, M</creator><creator>Souweine, B</creator><creator>Tridon, A</creator><creator>Cordier, J-F</creator><creator>Aumaître, O</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>200812</creationdate><title>Intra-alveolar haemorrhage without renal damage as the initial presenting feature of Goodpasture's syndrome: case report and review of literature</title><author>Lê Quang, C ; 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We report a 36-year-old woman with pulmonary haemorrhage and review 28 additional cases of the literature. In fact, these patients had often mild urine abnormalities and constant glomerular lesions. Antiglomerular basement membrane antibodies testing should be systematically ordered in patients presenting with alveolar haemorrhage. Goodpasture's syndrome without renal abnormality could be an early stage of the disease with a better prognosis.</abstract><cop>France</cop><pmid>18572276</pmid><doi>10.1016/j.revmed.2008.03.001</doi></addata></record> |
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subjects | Adolescent Adrenal Cortex Hormones - administration & dosage Adrenal Cortex Hormones - therapeutic use Adult Anti-Glomerular Basement Membrane Disease - diagnosis Anti-Glomerular Basement Membrane Disease - drug therapy Anti-Glomerular Basement Membrane Disease - immunology Anti-Glomerular Basement Membrane Disease - pathology Anti-Glomerular Basement Membrane Disease - therapy Autoantibodies - analysis Biopsy Bronchoalveolar Lavage Cyclophosphamide - administration & dosage Cyclophosphamide - therapeutic use Drug Therapy, Combination Female Follow-Up Studies Glomerular Basement Membrane - immunology Glomerular Basement Membrane - pathology Hemorrhage - diagnosis Hemorrhage - etiology Humans Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - therapeutic use Lung Diseases - diagnostic imaging Lung Diseases - etiology Male Plasma Exchange Prognosis Pulmonary Alveoli Radiography, Thoracic Time Factors Tomography, X-Ray Computed Treatment Outcome |
title | Intra-alveolar haemorrhage without renal damage as the initial presenting feature of Goodpasture's syndrome: case report and review of literature |
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