Intra-alveolar haemorrhage without renal damage as the initial presenting feature of Goodpasture's syndrome: case report and review of literature

Isolated pulmonary involvement in Goodpasture's syndrome is exceptionally described. We report a 36-year-old woman with pulmonary haemorrhage and review 28 additional cases of the literature. In fact, these patients had often mild urine abnormalities and constant glomerular lesions. Antiglomeru...

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Veröffentlicht in:La revue de medecine interne 2008-12, Vol.29 (12), p.1038
Hauptverfasser: Lê Quang, C, Delèvaux, I, Trouillier, S, André, M, Souweine, B, Tridon, A, Cordier, J-F, Aumaître, O
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Sprache:fre
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Zusammenfassung:Isolated pulmonary involvement in Goodpasture's syndrome is exceptionally described. We report a 36-year-old woman with pulmonary haemorrhage and review 28 additional cases of the literature. In fact, these patients had often mild urine abnormalities and constant glomerular lesions. Antiglomerular basement membrane antibodies testing should be systematically ordered in patients presenting with alveolar haemorrhage. Goodpasture's syndrome without renal abnormality could be an early stage of the disease with a better prognosis.
ISSN:0248-8663
DOI:10.1016/j.revmed.2008.03.001