Terbinafine-Induced Subacute Cutaneous Lupus Erythematosus

Terbinafine is a synthetic oral allylamine that is used for systemic treatment of microscopy- or culture-proven dermatophyte infections of skin and nails. It is normally well-tolerated and side effects include transient gastrointestinal symptoms and skin reactions that can occur in up to 2.3% of tre...

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Veröffentlicht in:Cutis (New York, N.Y.) N.Y.), 2008-02, Vol.81 (2), p.156-157
Hauptverfasser: HIVNOR, Chad M, HUDKINS, Matthew L, BONNER, Bert
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Sprache:eng
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Zusammenfassung:Terbinafine is a synthetic oral allylamine that is used for systemic treatment of microscopy- or culture-proven dermatophyte infections of skin and nails. It is normally well-tolerated and side effects include transient gastrointestinal symptoms and skin reactions that can occur in up to 2.3% of treated patients. Subacute cutaneous lupus erythematosus (SCLE) is a skin reaction that has been reported secondary to use of a variety of drugs. The number of reports of SCLE with terbinafine is limited. We demonstrate 2 patients in one dermatology clinic who presented with a predisposing autoimmune diathesis within 3 months of each other.
ISSN:0011-4162
2326-6929