Comparison of Nasal Swabs with Nose Blowing for Community-Based Pneumococcal Surveillance of Healthy Children

The nasopharynx (NP) is the preferred site for detection of Streptococcus pneumoniae in young children, but NP sampling is not well tolerated. We compared nose blowing with paired nasal swabs. The sensitivity of nose blowing was 46% (95% confidence interval [CI] 38 to 56%), which increased to 94% (9...

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Veröffentlicht in:	Journal of Clinical Microbiology 2008-06, Vol.46 (6), p.2081-2082
Hauptverfasser:	Leach, Amanda Jane, Stubbs, Elizabeth, Hare, Kim, Beissbarth, Jemima, Morris, Peter Stanley
Format:	Artikel
Sprache:	eng
Schlagworte:	Australia Bacteriology Biological and medical sciences Carrier State - epidemiology Carrier State - microbiology Child Child Day Care Centers Child, Preschool Fundamental and applied biological sciences. Psychology Humans Microbiology Miscellaneous Nasopharynx - metabolism Nasopharynx - microbiology Pneumococcal Infections - epidemiology Pneumococcal Infections - microbiology Population Surveillance Rural Population Sensitivity and Specificity Specimen Handling - methods Streptococcus pneumoniae Streptococcus pneumoniae - isolation & purification Urban Population
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Beschreibung
Zusammenfassung:	The nasopharynx (NP) is the preferred site for detection of Streptococcus pneumoniae in young children, but NP sampling is not well tolerated. We compared nose blowing with paired nasal swabs. The sensitivity of nose blowing was 46% (95% confidence interval [CI] 38 to 56%), which increased to 94% (95% CI, 85 to 98%) for children with visible secretions.
ISSN:	0095-1137 1098-660X 1098-660X 1098-5530
DOI:	10.1128/JCM.00048-08