In vitro antiviral activity of plant extracts on goatpox virus replication
Four plants having known medicinal properties were screened for inhibition of goatpox virus (GTPV) replication in vitro. Of the 4 plants, extract of Acacia arabica (Babul) and Eugenia jambolana (Jamun) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99.93 +/- 0.3...
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| Veröffentlicht in: | Indian journal of experimental biology 2008-02, Vol.46 (2), p.120 |
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| container_title | Indian journal of experimental biology |
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| creator | Bhanuprakash, V Hosamani, M Balamurugan, V Gandhale, P Naresh, Ram Swarup, D Singh, R K |
| description | Four plants having known medicinal properties were screened for inhibition of goatpox virus (GTPV) replication in vitro. Of the 4 plants, extract of Acacia arabica (Babul) and Eugenia jambolana (Jamun) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99.93 +/- 0.38 and 1999.73 +/- 0.50 microg/ml, respectively in all cytopathic effect (CPE) inhibition assays. Inhibition of GTPV virus replication was further confirmed by PCR and SYBR Green based quantitative real-time QPCR assays specific for GTPV. Results indicated that the extract of Acacia arabica and Eugenia jambolana leaves inhibited GTPV replication in vitro. |
| format | Article |
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Of the 4 plants, extract of Acacia arabica (Babul) and Eugenia jambolana (Jamun) leaves had inhibition (%) 99.70 and 99.92 at their maximum non toxic concentrations, 99.93 +/- 0.38 and 1999.73 +/- 0.50 microg/ml, respectively in all cytopathic effect (CPE) inhibition assays. Inhibition of GTPV virus replication was further confirmed by PCR and SYBR Green based quantitative real-time QPCR assays specific for GTPV. 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| ispartof | Indian journal of experimental biology, 2008-02, Vol.46 (2), p.120 |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | Acacia Animals Antiviral Agents - isolation & purification Antiviral Agents - pharmacology Capripoxvirus - drug effects Cercopithecus aethiops Cytopathogenic Effect, Viral - drug effects In Vitro Techniques Plant Extracts - pharmacology Plant Leaves Poxviridae Infections - drug therapy Syzygium Vero Cells Virus Replication - drug effects |
| title | In vitro antiviral activity of plant extracts on goatpox virus replication |
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