Alteration of deposition pattern and pulmonary response as a result of improved dispersion of aspirated single-walled carbon nanotubes in a mouse model

1 Pathology and Physiology Research Branch, Health Effect Laboratory Division, National Institute for Occupational Safety and Health, Morgantown; and 2 Department of Physiology and Pharmacology, West Virginia University, Morgantown, West Virginia Submitted 10 May 2007 ; accepted in final form 11 Nov...

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Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2008-01, Vol.294 (1), p.L87-L97
Hauptverfasser:	Mercer, R. R, Scabilloni, J, Wang, L, Kisin, E, Murray, A. R, Schwegler-Berry, D, Shvedova, A. A, Castranova, V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Weight Carbon Carbon - pharmacokinetics Carbon - pharmacology Gases - metabolism Hypothesis testing Inhalation - physiology Lung - anatomy & histology Lung - drug effects Lung - physiology Lung - ultrastructure Lungs Mice Microscopy, Confocal Microscopy, Electron, Scanning Microscopy, Fluorescence Models, Animal Nanoparticles Nanotubes Neutrophils - drug effects Neutrophils - physiology Neutrophils - ultrastructure Organ Size Pulmonary Alveoli - anatomy & histology Rodents Surface Properties
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Zusammenfassung:	1 Pathology and Physiology Research Branch, Health Effect Laboratory Division, National Institute for Occupational Safety and Health, Morgantown; and 2 Department of Physiology and Pharmacology, West Virginia University, Morgantown, West Virginia Submitted 10 May 2007 ; accepted in final form 11 November 2007 Nanoparticles have a fundamental dimension of
ISSN:	1040-0605 1522-1504
DOI:	10.1152/ajplung.00186.2007