Allergy to penicillins and to cephalosporins: should we fear cross-reactivity?

Allergy to penicillins and to cephalosporins: should we fear cross-reactivity?

The diagnosis of allergy to penicillins is based on a positive history and cutaneous tests. The sensitivity of these tests is around 70%, therefore it is sometimes necessary to supplement them with in vitro tests, more rarely with drug provocation challenges. Among patients allergic to penicillin, 1...

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Veröffentlicht in:Revue médicale suisse 2007-10, Vol.3 (129), p.2339
Hauptverfasser: Iten, A, Plojoux, J, Taramarcaz, P
Format: Artikel
Sprache:fre
Schlagworte:
Cephalosporins - adverse effects
Cross Reactions
Drug Hypersensitivity
Humans
Penicillins - adverse effects
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Zusammenfassung:The diagnosis of allergy to penicillins is based on a positive history and cutaneous tests. The sensitivity of these tests is around 70%, therefore it is sometimes necessary to supplement them with in vitro tests, more rarely with drug provocation challenges. Among patients allergic to penicillin, 1 to 2% will develop an allergy to cephalosporins in the event of exposure to this antibiotic class. In this paper, we describe options for investigating and treating allergy to penicillins and cephalosporins.
ISSN:1660-9379