Pregnancies complicated by multidrug-resistant tuberculosis and HIV co-infection in Durban, South Africa [Short Communication]

SETTING: Tertiary hospitals in KwaZulu Natal, South Africa.OBJECTIVE: To study the impact of multidrug-resistant tuberculosis (MDR-TB) and human immunodeficiency virus-1 (HIV-1) co-infection during pregnancy on maternal and perinatal outcome.DESIGN: Prospective study performed between 1996 and 2001....

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Veröffentlicht in:	The international journal of tuberculosis and lung disease 2007-06, Vol.11 (6), p.706-708
Hauptverfasser:	KHAN, M, PILLAY, T, MOODLEY, J, RAMJEE, A, PADAYATCHI, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Induced Abortion, Spontaneous Adolescent Adult Antitubercular Agents - adverse effects Bacterial diseases Biological and medical sciences Female Fetal Growth Retardation - etiology HIV Infections - complications HIV Infections - diagnosis HIV Infections - transmission HIV Infections - virology HIV-1 Human bacterial diseases Human immunodeficiency virus 1 Humans Infectious Disease Transmission, Vertical Infectious diseases Live Birth Maternal And Perinatal Outcomes Medical sciences Miscellaneous Multidrug-Resistant Tuberculosis Mycobacterium tuberculosis - isolation & purification Pneumology Pregnancy Pregnancy Complications, Infectious - diagnosis Pregnancy Complications, Infectious - drug therapy Pregnancy Complications, Infectious - microbiology Pregnancy Complications, Infectious - virology Prevention and actions Prospective Studies Public health. Hygiene Public health. Hygiene-occupational medicine South Africa Sputum - microbiology Tuberculosis and atypical mycobacterial infections Tuberculosis, Multidrug-Resistant - complications Tuberculosis, Multidrug-Resistant - diagnosis Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Multidrug-Resistant - microbiology Tuberculosis, Multidrug-Resistant - transmission
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Beschreibung
Zusammenfassung:	SETTING: Tertiary hospitals in KwaZulu Natal, South Africa.OBJECTIVE: To study the impact of multidrug-resistant tuberculosis (MDR-TB) and human immunodeficiency virus-1 (HIV-1) co-infection during pregnancy on maternal and perinatal outcome.DESIGN: Prospective study performed between 1996 and 2001. Symptomatic pregnant women were investigated for TB. Those with confirmed MDR-TB were reported on.RESULTS: Three of five pregnant women with MDR-TB were HIV-1 co-infected. One woman decided to terminate the pregnancy and one experienced pre-term labour. Two neonates had features of growth restriction.CONCLUSION: Management of pregnant women with MDR-TB in an HIV-endemic area is possible in developing countries.
ISSN:	1027-3719 1815-7920