Hodgkin lymphoma in Chile: experience of the national adult cancer program

Hodgkin lymphoma is a highly curable disease. To evaluate the clinical characteristics and the treatment results of Hodgkin lymphoma patients of the National Cancer Program in Chile. Prospective assessment of 682 patients treated in 18 adult cancer centers. Progression free survival (PFS) and overal...

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Veröffentlicht in:	Revista medíca de Chile 2007-03, Vol.135 (3), p.341
Hauptverfasser:	Cabrera, M Elena, García, Hernán, Lois, Vivian, León, Alvaro, Peña, Karina, Rossle, Alberto, Cerda, Berta, Rojas, Hernán, Meneses, Pedro, Merino, Carlos, Aspillaga, Augusto, Vittini de, Cecilia, Oliva, Jacqueline, Hales, Cecilia, Rosas, Janet
Format:	Artikel
Sprache:	spa
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use Bleomycin - administration & dosage Chi-Square Distribution Chile Cyclophosphamide - administration & dosage Dacarbazine - administration & dosage Disease-Free Survival Doxorubicin - administration & dosage Female Follow-Up Studies Hodgkin Disease - drug therapy Hodgkin Disease - radiotherapy Humans Male Middle Aged Mitoxantrone - administration & dosage National Health Programs Prednisolone - administration & dosage Prednisone - administration & dosage Procarbazine - administration & dosage Prospective Studies Treatment Outcome Vinblastine - administration & dosage Vincristine - administration & dosage
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Zusammenfassung:	Hodgkin lymphoma is a highly curable disease. To evaluate the clinical characteristics and the treatment results of Hodgkin lymphoma patients of the National Cancer Program in Chile. Prospective assessment of 682 patients treated in 18 adult cancer centers. Progression free survival (PFS) and overall survival (OS) were calculated. Median follow up was 127, 95, 87, 72 and 50 months for C-MOPP, radiotherapy (RT), C-MOPP/ABV, NOVP and ABVD, respectively. Median age was 37 years (15-84). Nodular sclerosis and mixed cellularity were equally expressed. Advanced stages (III & IV) were present at diagnosis in 61% of cases. Age over 40 was an adverse prognostic factor (p
ISSN:	0034-9887