Oral cefadroxil prophylaxis in hip fracture surgery: Serum concentrations studied in 17 patients
Serum concentration-time curves were determined in seventeen 82 (60-90) year-old patients undergoing trochanteric hip fracture surgery after receiving 1 g of cefadroxil per os. All the patients attained a serum level of antibiotic high enough to inhibit the growth of Staphylococcus aureus and S. epi...
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| Veröffentlicht in: | Acta orthopaedica Scandinavica 1992-02, Vol.63 (1), p.4-6 |
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| container_title | Acta orthopaedica Scandinavica |
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| creator | Nungu, Kitugi Samwel Bengtsson, Stellan Olerud, Claes Rehnberg, Lars Larsson, Sune |
| description | Serum concentration-time curves were determined in seventeen 82 (60-90) year-old patients undergoing trochanteric hip fracture surgery after receiving 1 g of cefadroxil per os. All the patients attained a serum level of antibiotic high enough to inhibit the growth of Staphylococcus aureus and S. epidermidis. When orally administered, cefadroxil should be given within 2 hours before surgery. Serum concentrations studied in 17 patients |
| doi_str_mv | 10.3109/17453679209154839 |
| format | Article |
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All the patients attained a serum level of antibiotic high enough to inhibit the growth of Staphylococcus aureus and S. epidermidis. When orally administered, cefadroxil should be given within 2 hours before surgery. Serum concentrations studied in 17 patients</description><identifier>ISSN: 0001-6470</identifier><identifier>DOI: 10.3109/17453679209154839</identifier><identifier>PMID: 1738968</identifier><identifier>CODEN: AOSAAK</identifier><language>eng</language><publisher>Basingstoke: Taylor & Francis</publisher><subject>Aged ; Aged, 80 and over ; Antibacterial agents ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Biological and medical sciences ; Cefadroxil - blood ; Cefadroxil - therapeutic use ; Female ; Hip Fractures - surgery ; Humans ; Male ; Medical sciences ; Middle Aged ; Pharmacology. 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All the patients attained a serum level of antibiotic high enough to inhibit the growth of Staphylococcus aureus and S. epidermidis. When orally administered, cefadroxil should be given within 2 hours before surgery. Serum concentrations studied in 17 patients</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antibacterial agents</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Biological and medical sciences</subject><subject>Cefadroxil - blood</subject><subject>Cefadroxil - therapeutic use</subject><subject>Female</subject><subject>Hip Fractures - surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pharmacology. Drug treatments</subject><subject>Premedication</subject><subject>Staphylococcus aureus - drug effects</subject><subject>Staphylococcus epidermidis - drug effects</subject><subject>Surgical Wound Infection - prevention & control</subject><subject>Time Factors</subject><issn>0001-6470</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kEtLxDAUhbNQxnH0B7gQuhB31dwmTRpwI4MvGJiNrkuSJk4kfZi0aP-9HWbUhbi6XM53DoeD0BngKwJYXAOnOWFcZFhATgsiDtAcYwwpoxwfoeMY37YvMD5DM-CkEKyYI7IO0ifaWFmF9tP5pAtttxm9_HQxcU2ycV1ig9T9EEwSh_BqwniCDq300Zzu7wK93N89Lx_T1frhaXm7SjXJaZ9SJjJZUQzEUsMZVizLuM6t5oQpanMjZCbAFoWRshCqMrYCC4YqxZQSWpMFutzlTp3eBxP7snZRG-9lY9ohljwrcA4MTyDsQB3aGIOxZRdcLcNYAi6345R_xpk85_vwQdWm-nXslpn0i70uo5Z-2qDRLv5gOQAGscVudphrbBtq-dEGX5W9HH0bvj3k_xZfKu-A9A</recordid><startdate>19920201</startdate><enddate>19920201</enddate><creator>Nungu, Kitugi Samwel</creator><creator>Bengtsson, Stellan</creator><creator>Olerud, Claes</creator><creator>Rehnberg, Lars</creator><creator>Larsson, Sune</creator><general>Taylor & Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19920201</creationdate><title>Oral cefadroxil prophylaxis in hip fracture surgery</title><author>Nungu, Kitugi Samwel ; Bengtsson, Stellan ; Olerud, Claes ; Rehnberg, Lars ; Larsson, Sune</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c354t-4692ad4013f4e760b6227c5fc736b4f5e9a291f88eaa89bdefd1f1e4bb6bb9cc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Antibacterial agents</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Biological and medical sciences</topic><topic>Cefadroxil - blood</topic><topic>Cefadroxil - therapeutic use</topic><topic>Female</topic><topic>Hip Fractures - surgery</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pharmacology. 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| fulltext | fulltext |
| identifier | ISSN: 0001-6470 |
| ispartof | Acta orthopaedica Scandinavica, 1992-02, Vol.63 (1), p.4-6 |
| issn | 0001-6470 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Aged Aged, 80 and over Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Cefadroxil - blood Cefadroxil - therapeutic use Female Hip Fractures - surgery Humans Male Medical sciences Middle Aged Pharmacology. Drug treatments Premedication Staphylococcus aureus - drug effects Staphylococcus epidermidis - drug effects Surgical Wound Infection - prevention & control Time Factors |
| title | Oral cefadroxil prophylaxis in hip fracture surgery: Serum concentrations studied in 17 patients |
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