Characterization and Bioscreening of a New Triterpenoid and a Flavanone Isolated from Salvia nubicola

Characterization and Bioscreening of a New Triterpenoid and a Flavanone Isolated from Salvia nubicola

A new epimeric lupane triterpenoid, 3α‐hydroxy‐20‐oxo‐30‐norlupane (1), and a new flavanone (nubatin; 3) have been isolated from Salvia nubicola collected from Quetta, Pakistan. The structures of these constituents were elucidated with the aid of spectroscopic techniques, including two‐dimensional N...

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Veröffentlicht in:Chemistry & biodiversity 2005-07, Vol.2 (7), p.910-916
Hauptverfasser: Ali, Muhammad S., Ahmed, Shakeel, Ibrahim, Syed A., Tareen, Rasool B.
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Antifungal Agents - chemistry
Antifungal Agents - pharmacology
Araceae - drug effects
Flavanones - chemistry
Flavanones - pharmacology
Flavones - chemistry
Flavones - pharmacology
Herbicides - chemistry
Herbicides - pharmacology
Molecular Structure
Salvia - chemistry
Triterpenes - chemistry
Triterpenes - pharmacology
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Zusammenfassung:A new epimeric lupane triterpenoid, 3α‐hydroxy‐20‐oxo‐30‐norlupane (1), and a new flavanone (nubatin; 3) have been isolated from Salvia nubicola collected from Quetta, Pakistan. The structures of these constituents were elucidated with the aid of spectroscopic techniques, including two‐dimensional NMR and NOE experiments. Both the metabolites were found to be moderately bio‐active.
ISSN:1612-1872
1612-1880
DOI:10.1002/cbdv.200590067