The role of CD44 adhesion molecule in oral cavity cancer

CD44 is an adhesion molecule, member of the transmembrane glucoprotein family, with large number of isoforms identified in many human tissues, with particularly high expression in proliferating cells and squamous cell epithelium. This review is focused on the role of CD44 in the carcinogenesis of th...

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Veröffentlicht in:	Experimental oncology 2006-06, Vol.28 (2), p.94
Hauptverfasser:	Georgolios, A, Batistatou, A, Charalabopoulos, A, Manolopoulos, L, Charalabopoulos, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - analysis Biomarkers, Tumor - metabolism Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - etiology Carcinoma, Squamous Cell - metabolism Humans Hyaluronan Receptors - analysis Hyaluronan Receptors - metabolism Hyaluronan Receptors - physiology Mouth Neoplasms - diagnosis Mouth Neoplasms - etiology Mouth Neoplasms - metabolism Prognosis
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Beschreibung
Zusammenfassung:	CD44 is an adhesion molecule, member of the transmembrane glucoprotein family, with large number of isoforms identified in many human tissues, with particularly high expression in proliferating cells and squamous cell epithelium. This review is focused on the role of CD44 in the carcinogenesis of the oral cavity with special emphasis on its potential use for diagnosis and prognosis of cancer of oral cavity.
ISSN:	1812-9269