Pharmacokinetics of Denopamine in Hemodialysis Patients

Pharmacokinetics of Denopamine in Hemodialysis Patients

The pharmacokinetics of denopamine on a hemodialysis day and on an interdialysis day was evaluated in 11 hemodialysis patients. Tmax was the only pharmacokinetical parameter that differed significantly between healthy volunteers and hemodialysis patients. It is suggested that denopamine can be admin...

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Veröffentlicht in:Renal failure 1991, Vol.13 (1), p.37-41
Hauptverfasser: Nakahama, Hajime, Izumi, Masaaki, Tanaka, Yoshimu, Wada, Akira, Fujita, Yoshimasa, Orita, Yoshimasa, Shirai, Dairoku, Kamada, Takenobu
Format: Artikel
Sprache:eng
Schlagworte:
Adrenergic beta-Agonists - pharmacokinetics
Adult
Biological and medical sciences
Cardiotonic agents
Cardiovascular system
Denopamine
Ethanolamines - pharmacokinetics
Hemodialysis
Humans
Hypotension - etiology
Male
Medical sciences
Pharmacokinetics
Pharmacology. Drug treatments
Regression Analysis
Renal Dialysis - adverse effects
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Zusammenfassung:The pharmacokinetics of denopamine on a hemodialysis day and on an interdialysis day was evaluated in 11 hemodialysis patients. Tmax was the only pharmacokinetical parameter that differed significantly between healthy volunteers and hemodialysis patients. It is suggested that denopamine can be administered to hemodialysis patients both on hemodialysis days and on interdialysis days without dosage adjustments.
ISSN:0886-022X
1525-6049
DOI:10.3109/08860229109022145