Rhabdomyolysis induced by fenofibrate monotherapy

Rhabdomyolysis with fibrate have been reported when fibrate are associated with statin or during renal insufficiency or hypothyroidism. We describe one patient with diabetes mellitus treated by fenofibrate monotherapy since several years; 48 h after gliclazide therapy was introduced, rhabdomyolysis...

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Veröffentlicht in:	La revue de medecine interne 2006-07, Vol.27 (7), p.573
Hauptverfasser:	Archambeaud-Mouveroux, F, Lopez, S, Combes, C, Lassandre, S, Amaniou, M, Teissier, M-P, Galinat, S
Format:	Artikel
Sprache:	fre
Schlagworte:	Diabetes Mellitus - drug therapy Drug Interactions Dyslipidemias - drug therapy Fenofibrate - adverse effects Follow-Up Studies Gliclazide - adverse effects Humans Hypoglycemic Agents - adverse effects Hypolipidemic Agents - adverse effects Male Middle Aged Rhabdomyolysis - chemically induced
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Zusammenfassung:	Rhabdomyolysis with fibrate have been reported when fibrate are associated with statin or during renal insufficiency or hypothyroidism. We describe one patient with diabetes mellitus treated by fenofibrate monotherapy since several years; 48 h after gliclazide therapy was introduced, rhabdomyolysis occurred. Responsibilities of deshydratation and / or drug interaction with gliclazide. are discussed.
ISSN:	0248-8663
DOI:	10.1016/j.revmed.2006.02.013