Evaluation of Diagnostic Assays for Hepatitis E Virus in Outbreak Settings

Hepatitis E virus (HEV) is a major cause of hepatitis. We evaluated five HEV antibody diagnostic assays by using outbreak specimens. The Abbott immunoglobulin G (IgG), Genelabs IgG, and Walter Reed Army Institute of Research (WRAIR) IgM assays were about 90% sensitive; the Abbott IgG and WRAIR total...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of Clinical Microbiology 2006-04, Vol.44 (4), p.1581-1583
Hauptverfasser:	Myint, Khin Saw Aye, Endy, Timothy P, Gibbons, Robert V, Laras, Kanti, Mammen, Mammen P, Sedyaningsih, Endang R, Seriwatana, Jitvimol, Glass, Jonathan S, Narupiti, Sumitda, Corwin, Andrew L
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cross-Sectional Studies Disease Outbreaks DNA, Viral - analysis Fundamental and applied biological sciences. Psychology Hepatitis Antibodies - blood Hepatitis E - diagnosis Hepatitis E - epidemiology Hepatitis E - immunology Hepatitis E virus Hepatitis E virus - genetics Hepatitis E virus - isolation & purification Humans Immunoenzyme Techniques - methods Immunoenzyme Techniques - standards Infectious diseases Medical sciences Microbiology Miscellaneous Retrospective Studies Virology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Hepatitis E virus (HEV) is a major cause of hepatitis. We evaluated five HEV antibody diagnostic assays by using outbreak specimens. The Abbott immunoglobulin G (IgG), Genelabs IgG, and Walter Reed Army Institute of Research (WRAIR) IgM assays were about 90% sensitive; the Abbott IgG and WRAIR total Ig and IgM assays were more than 90% specific.
ISSN:	0095-1137 1098-660X 1098-5530
DOI:	10.1128/JCM.44.4.1581-1583.2006