Improved isotopic deuterium labeling at the diastereotopic methyl group of leucine: a synthetic route to (4S)- and (4R)-(5-2H1) leucine

Two isotopomers of deuterium-labeled leucine in the diastereotopic methyl group were synthesized from inexpensively available (R)- and (S)-citronellol in a more convenient way than by previous methods.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2006-01, Vol.70 (1), p.276-278
Hauptverfasser:	Yamauchi, N.(Kyushu Univ., Fukuoka (Japan)), Endoh, S
Format:	Artikel
Sprache:	eng
Schlagworte:	BIOCHEMISTRY BIOCHIMIE Biological and medical sciences BIOQUIMICA CHEMICAL STRUCTURE CHEMICAL SYNTHESIS DEUTERIO DEUTERIUM Deuterium - chemistry deuterium labeling diastereotopic methyl group ESTRUCTURA QUIMICA EXPERIMENTACION EN LABORATORIO EXPERIMENTATION EN LABORATOIRE Fundamental and applied biological sciences. Psychology Isotope Labeling - methods LABORATORY EXPERIMENTATION LEUCINA LEUCINE Leucine - analogs & derivatives Leucine - chemical synthesis Leucine - chemistry Methylation Molecular Structure SINTESIS QUIMICA Stereoisomerism STRUCTURE CHIMIQUE SYNTHESE CHIMIQUE TECHNIQUE DES TRACEURS TECNICAS DE TRAZADORES TRACER TECHNIQUES
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Two isotopomers of deuterium-labeled leucine in the diastereotopic methyl group were synthesized from inexpensively available (R)- and (S)-citronellol in a more convenient way than by previous methods.
ISSN:	0916-8451 1347-6947
DOI:	10.1271/bbb.70.276