Suppressive effect of astaxanthin isolated from the Xanthophyllomyces dendrorhous [Phaffia rhodozyma] mutant on ethanol-induced gastric mucosal injury in rats

Ethanol has been found to induce ulcerative gastric lesion in humans. The present study investigated the in vivo protective effect of astaxanthin isolated from the Xanthophyllomyces dendrorhous mutant against ethanolinduced gastric mucosal injury in rats. The rats were treated with 80% ethanol for 3...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2005-07, Vol.69 (7), p.1300-1305
Hauptverfasser:	Kim, J.H. (Korea Univ., Seoul (Korea R.)), Choi, S.K, Choi, S.Y, Kim, H.K, Chang, H.I
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals anti-ulcer drug astaxanthin Basidiomycota - chemistry Basidiomycota - genetics beta Carotene - administration & dosage beta Carotene - analogs & derivatives beta Carotene - isolation & purification beta Carotene - pharmacology Biological and medical sciences CATALASE Catalase - metabolism Dose-Response Relationship, Drug DRUGS ETHANOL Ethanol - toxicity Fundamental and applied biological sciences. Psychology Gastric Mucosa - drug effects Gastric Mucosa - metabolism Gastric Mucosa - pathology gastric mucosal injury GLUTATHIONE PEROXIDASE Glutathione Peroxidase - metabolism Male Malondialdehyde - metabolism Models, Biological MUCOSAL DISEASE Mutation orogastric administration PHAFFIA RHODOZYMA RATS Rats, Sprague-Dawley Severity of Illness Index STOMACH ULCER Stomach Ulcer - chemically induced Stomach Ulcer - metabolism Stomach Ulcer - prevention & control SUPEROXIDE DISMUTASE Superoxide Dismutase - metabolism Xanthophyllomyces dendrorhous XANTHOPHYLLS
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