No adverse effects of adjuvant chemotherapy on hippocampal volume in japanese breast cancer survivors

We investigated the adverse effects of adjuvant chemotherapy on the hippocampus in Japanese breast cancer survivors with (n=44) and without (n=31) adjuvant chemotherapy. There were no significant differences in hippocampal volume (magnetic resonance imaging) or additionally in memory function (Wechs...

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Veröffentlicht in:	Breast cancer research and treatment 2005-07, Vol.92 (1), p.81-84
Hauptverfasser:	YOSHIKAWA, Eisho, MATSUOKA, Yutaka, MURAKAMI, Koji, UCHITOMI, Yosuke, INAGAKI, Masatoshi, NAKANO, Tomohito, AKECHI, Tatsuo, KOBAYAKAWA, Makoto, FUJIMORI, Maiko, NAKAYA, Naoki, AKIZUKI, Nobuya, IMOTO, Shigeru
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - adverse effects Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Biological and medical sciences Breast Neoplasms - drug therapy Breast Neoplasms - surgery Female Gynecology. Andrology. Obstetrics Hippocampus - drug effects Humans Japan Magnetic Resonance Imaging Mammary gland diseases Mastectomy Medical sciences Memory Disorders - chemically induced Memory Disorders - diagnosis Middle Aged Neuropsychological Tests Organ Size - drug effects Survivors Tumors
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Zusammenfassung:	We investigated the adverse effects of adjuvant chemotherapy on the hippocampus in Japanese breast cancer survivors with (n=44) and without (n=31) adjuvant chemotherapy. There were no significant differences in hippocampal volume (magnetic resonance imaging) or additionally in memory function (Wechsler Memory Scale-Revised) between the two groups.
ISSN:	0167-6806 1573-7217
DOI:	10.1007/s10549-005-1412-6