Heroin abuse and methadone substitution in pregnancy

The pre- and postnatal data of 20 pregnant heroin addicts and their neonates are described. 16 women were treated with methadone to prevent withdrawal symptoms. A relatively stabile prenatal condition with a decrease of complications was achieved. On the other hand, the neonates suffered from severe...

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Veröffentlicht in:	Geburtshilfe und Frauenheilkunde 1992-03, Vol.52 (3), p.144
Hauptverfasser:	Vering, A, Seeger, J, Becker, S, Halberstadt, E, Bender, H G
Format:	Artikel
Sprache:	ger
Schlagworte:	Asphyxia Neonatorum - etiology Cardiotocography - drug effects Dose-Response Relationship, Drug Female Fetal Growth Retardation - etiology Heroin - adverse effects Heroin Dependence - rehabilitation HIV Infections - etiology Humans Infant, Newborn Methadone - adverse effects Neonatal Abstinence Syndrome - etiology Neurologic Examination Pregnancy Pregnancy Complications - rehabilitation Spasms, Infantile - etiology
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Zusammenfassung:	The pre- and postnatal data of 20 pregnant heroin addicts and their neonates are described. 16 women were treated with methadone to prevent withdrawal symptoms. A relatively stabile prenatal condition with a decrease of complications was achieved. On the other hand, the neonates suffered from severe withdrawal symptoms including seizures in spite of intensive paediatric care and prophylactic treatment with barbiturates. After a mean follow-up of one to two years a relatively good neurological development of the children was observed.
ISSN:	0016-5751