Successful treatment of surgically induced necrotizing scleritis with tacrolimus

Successful treatment of surgically induced necrotizing scleritis with tacrolimus

A 46‐year‐old man developed surgically induced necrotizing scleritis (SINS) 7 months following uneventful primary bare sclera pterygium excision. The patient underwent two scleral patch grafts for SINS but despite the use of cyclophos­phamide and azathioprine, the scleral patch grafts failed within...

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Veröffentlicht in:Clinical & experimental ophthalmology 2005-02, Vol.33 (1), p.98-99
Hauptverfasser: Young, Alvin L, Wong, SM, Leung, Alfred TS, Leung, Gloria YS, Cheng, Lulu L, Lam, Dennis SC
Format: Artikel
Sprache:eng
Schlagworte:
FK506
Graft Survival - drug effects
Humans
Immunosuppressive Agents - therapeutic use
Male
Middle Aged
Ophthalmologic Surgical Procedures - adverse effects
patch graft
Pterygium - surgery
Recurrence
Reoperation
Sclera - transplantation
Scleritis - drug therapy
Scleritis - etiology
surgically induced necrotizing scleritis
tacrolimus
Tacrolimus - therapeutic use
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container_end_page 99
container_issue 1
container_start_page 98
container_title Clinical & experimental ophthalmology
container_volume 33
creator Young, Alvin L
Wong, SM
Leung, Alfred TS
Leung, Gloria YS
Cheng, Lulu L
Lam, Dennis SC
description A 46‐year‐old man developed surgically induced necrotizing scleritis (SINS) 7 months following uneventful primary bare sclera pterygium excision. The patient underwent two scleral patch grafts for SINS but despite the use of cyclophos­phamide and azathioprine, the scleral patch grafts failed within 1 month of surgery on both occasions. Tacrolimus was used for his third scleral patch graft. No recurrence of necrotizing scleritis was observed for 2 years. Tacrolimus may be considered as a valuable adjunctive immuno­suppressant in the management of resistant necrotizing scleritis.
doi_str_mv 10.1111/j.1442-9071.2005.00955.x
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects FK506
Graft Survival - drug effects
Humans
Immunosuppressive Agents - therapeutic use
Male
Middle Aged
Ophthalmologic Surgical Procedures - adverse effects
patch graft
Pterygium - surgery
Recurrence
Reoperation
Sclera - transplantation
Scleritis - drug therapy
Scleritis - etiology
surgically induced necrotizing scleritis
tacrolimus
Tacrolimus - therapeutic use
title Successful treatment of surgically induced necrotizing scleritis with tacrolimus
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